Evidence map›Paper›PMID 24166217›Full record

ArticleCancer2014

Costs and outcomes evaluation of patient navigation after abnormal cancer screening: evidence from the Patient Navigation Research Program.

Mark E Bensink, Scott D Ramsey, Tracy Battaglia, Kevin Fiscella, Thelma C Hurd, June M McKoy, Steven R Patierno, Peter C Raich, Eric E Seiber, Victoria Warren-Mears and 4 more

Abstract read
In one paragraph

Article in Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Adherence in the Cancer Care Setting: a Systematic Review of Patient Navigation to Traverse Barriers.Journal of cancer education : the official journal of the American Association for Cancer Education · 2018
    Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
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  7. Trial
  8. Article
  9. Review
  10. Barrier resolution via patient navigation in the context of cancer care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  11. Article
  12. Article
  13. Leveraging Patient Education to Amplify Colorectal Cancer Screening in the United States: Strategies and Implications.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Relationship between using cancer resource center services and patient outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mark E BensinkResearch and Economic Assessment in Cancer and Healthcare Group, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Scott D Ramsey
Tracy Battaglia
Kevin Fiscella
Thelma C Hurd
June M McKoy
Steven R Patierno
Peter C Raich
Eric E Seiber
Victoria Warren-Mears
Elizabeth Whitley
Electra D Paskett
S Mandelblatt
Patient Navigation Research Program

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
Comparative Modeling: Informing Breast Cancer Control Practice & PolicyU01CA152958 · NCI · GEORGETOWN UNIVERSITY · PI BERRY, DONALD A, DE KONING, HARRY J · 2010 to 2015
$7.6M
Chicago Cancer Navigation ProjectU01CA116875 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ROSEN, STEVEN TERRY · 2005 to 2011
$4.5M
RCT of Primary Care-based Patient Navigation-ActivationU01CA116924 · NCI · UNIVERSITY OF ROCHESTER · PI FISCELLA, KEVIN ANTHONY · 2005 to 2011
$4.4M
Randomized Trial of Lay Health Worker Smoking Cessation Intervention for LatinosU01CA114593 · NCI · MEDSTAR RESEARCH INSTITUTE · PI HUERTA, ELMER E · 2005 to 2009
$4.3M
"Patient Navigation in the SafetyNet: CONNECTeDD"U01CA116892 · NCI · BOSTON MEDICAL CENTER · PI FREUND, KAREN · 2005 to 2010
$4.3M
DC City-wide Patient Navigation Research ProgramU01CA116937 · NCI · GEORGE WASHINGTON UNIVERSITY · PI PATIERNO, STEVEN R · 2005 to 2011
$4.1M
Improving Patient Outcomes Through System NavigationU01CA116903 · NCI · DENVER HEALTH AND HOSPITAL AUTHORITY · PI RAICH, PETER CHRISTIAN · 2005 to 2011
$3.8M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthKL2TR001118 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, DOUGHERTY, DONALD M · 2013 to 2017
$3.4M
Patient Navigation Research ProgramU01CA116885 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DUDLEY, DONALD J · 2005 to 2010
$3.3M
Patient Navigator ProgramU01CA117281 · NCI · H. LEE MOFFITT CANCER CTR &RES INST · PI ROETZHEIM, RICHARD G · 2005 to 2009
$3.1M
NCATS NIH HHS KL2 TR001118NCATS NIH HHS UL1 TR001120NCI NIH HHS K01 CA134554NCI NIH HHS K05 CA096940NCI NIH HHS P30 CA016058NCI NIH HHS U01 CA088283NCI NIH HHS U01 CA114593NCI NIH HHS U01 CA116875NCI NIH HHS U01CA116875NCI NIH HHS U01 CA116885NCI NIH HHS U01CA116885NCI NIH HHS U01 CA116892NCI NIH HHS U01 CA116903NCI NIH HHS U01CA116903NCI NIH HHS U01 CA116924NCI NIH HHS U01CA116924NCI NIH HHS U01 CA116925NCI NIH HHS U01CA116925NCI NIH HHS U01 CA116937NCI NIH HHS U01CA116937NCI NIH HHS U01 CA117281NCI NIH HHS U01 CA152958
6 · The paper itself

Abstract

backgroundNavigators can facilitate timely access to cancer services, but to the authors' knowledge there are little data available regarding their economic impact.

methodsThe authors conducted a cost-consequence analysis of navigation versus usual care among 10,521 individuals with abnormal breast, cervical, colorectal, or prostate cancer screening results who enrolled in the Patient Navigation Research Program study from January 1, 2006 to March 31, 2010. Navigation costs included diagnostic evaluation, patient and staff time, materials, and overhead. Consequences or outcomes were time to diagnostic resolution and probability of resolution. Differences in costs and outcomes were evaluated using multilevel, mixed-effects regression modeling adjusting for age, race/ethnicity, language, marital status, insurance status, cancer, and site clustering.

resultsThe majority of individuals were members of a minority (70.7%) and uninsured or publically insured (72.7%). Diagnostic resolution was higher for navigation versus usual care at 180 days (56.2% vs 53.8%; P = .008) and 270 days (70.0% vs 68.2%; P < .001). Although there were no differences in the average number of days to resolution between the 2 groups (110 days vs 109 days; P = .63), the probability of ever having diagnostic resolution was higher for the navigation group versus the usual-care group (84.5% vs 79.6%; P < .001). The added cost of navigation versus usual care was $275 per patient (95% confidence interval, $260-$290; P < .001). There was no significant difference in stage distribution among the 12.4% of patients in the navigation group vs 11% of the usual-care patients diagnosed with cancer.

conclusionsNavigation adds costs and modestly increases the probability of diagnostic resolution among patients with abnormal screening test results. Navigation is only likely to be cost-effective if improved resolution translates into an earlier cancer stage at the time of diagnosis.

Indexed as

Cost-Benefit AnalysisEarly Detection of CancerFemaleHealthcare DisparitiesHumansMaleMass ScreeningMinority GroupsNeoplasmsTime Factorsabnormal cancer screeningcancercostnavigationoutcomes

Identifiers

PMID24166217
PMCPMC3946403

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.