Evidence map›Paper›PMID 24166035›Full record

ArticleOrganic & biomolecular chemistry2013

Synthesis of nitric oxide probes with fluorescence lifetime sensitivity.

Natalia G Zhegalova, Garrett Gonzales, Mikhail Y Berezin

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Natalia G ZhegalovaDepartment of Radiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA. berezinm@mir.wustl.edu.
Garrett Gonzales
Mikhail Y Berezin

Funding

DEVELOPMENT OF OPTICAL NANOTHERMOMETERS FOR MEDICAL APPLICATIONSR21CA149814 · NCI · WASHINGTON UNIVERSITY · PI BEREZIN, MIKHAIL Y. · 2010 to 2011
$353k
FLUORESCENCE SPECTROPHOTOMETER IN NIR RANGE FOR BIOLOGICAL AND MEDICAL APPLICATIOS10RR031621 · NCRR · WASHINGTON UNIVERSITY · PI BEREZIN, MIKHAIL Y. · 2011 to 2011
$292k
NCI NIH HHS R21 CA149814NCI NIH HHS R21CA149814NCRR NIH HHS 1S10RR031621-01NCRR NIH HHS S10 RR031621NHLBI NIH HHS HHSN268201000046C
6 · The paper itself

Abstract

We present the rationale, synthesis and evaluation of the first activatable fluorescent probe that utilizes fluorescence lifetime change for detection of nitric oxide. The new probe DAP-LT1 features a near-infrared polymethine skeleton with a diaminobenzene functionality incorporated into the meso-position. The probe is partially quenched, and upon reaction with nitric oxide shows an increase in the fluorescence lifetime from 1.08 ns to 1.24 ns.

Indexed as

FluorescenceCarbocyaninesFluorescent DyesIndolesMolecular StructureNitric OxideTime FactorsCarbocyaninesFluorescent DyesIndolesNitric Oxide

Identifiers

PMID24166035
PMCPMC3872128

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.