Evidence map›Paper›PMID 24165933›Full record

ArticleThe Journal of cell biology2013

The vesicular ATPase: a missing link between acidification and exocytosis.

Dong Wang, P Robin Hiesinger

Registry-linked trialAbstract readComment
In one paragraph

Article in The Journal of cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05711810 (Cardiac Transfer of SARS-CoV-2 Spike Protein Circulation Techniques - Medicine Induced Hemodialysis on "Vaccinated" Immune Attacks), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05711810 phase4completednot on this mapstarted 2023, after this paper: background citation

Cardiac Transfer of SARS-CoV-2 Spike Protein Circulation Techniques - Medicine Induced Hemodialysis on "Vaccinated" Immune Attacks

TypeinterventionalSponsorYang I. PachankisRan2023 to 2023Enrolled1ConditionsSevere Acute Respiratory Syndrome-related Coronavirus, Renal Dialysis, Vaccines, Myocarditis AllergicArmsNifedipine 30 MG, Kangzhu BPCB0A-3A, Low Mobility, Enalapril Maleate 10Mg Tab, Lansoprazole 30Mg Ec Cap
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Exploration of extracellular vesicles fromJournal of extracellular vesicles · 2019
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Vibrio effector protein VopQ inhibits fusion of V-ATPase-containing membranes.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Dong WangDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
P Robin Hiesinger

Funding

Regulation of Synaptic Specificity in the Visual System by Intracellular TraffickR01EY018884 · NEI · UT SOUTHWESTERN MEDICAL CENTER · PI HIESINGER, PETER ROBIN · 2008 to 2018
$3.6M
NEI NIH HHS R01 EY018884NEI NIH HHS R01EY018884
6 · The paper itself

Abstract

The vesicular adenosine triphosphatase (ATPase) acidifies intracellular compartments, including synaptic vesicles and secretory granules. A controversy about a second function of this ATPase in exocytosis has been fuelled by questions about multiple putative roles of acidification in the exocytic process. Now, Poëa-Guyon et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201303104) present new evidence that the vesicular ATPase performs separate acidification and exocytosis roles and propose a mechanism for how these two functions are causally linked.

Indexed as

ExocytosisSynaptic TransmissionAnimalsNeuronsSecretory VesiclesSynaptic VesiclesVacuolar Proton-Translocating ATPasesVacuolar Proton-Translocating ATPases

Identifiers

PMID24165933
PMCPMC3812979

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.