Evidence map›Paper›PMID 24165758›Full record

GuidelineGut2014

British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus.

Rebecca C Fitzgerald, Massimiliano di Pietro, Krish Ragunath, Yeng Ang, Jin-Yong Kang, Peter Watson, Nigel Trudgill, Praful Patel, Philip V Kaye, Scott Sanders and 12 more

2 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Gut, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 549 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
549citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03418584 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Application of hybridAPC in the Treatment of Barrett: a Multicenter, Prospective Study

TypeinterventionalSponsorChanghai HospitalRan2017 to 2021Enrolled80ConditionsBarrett's EsophagusArmsHybridAPC
NCT05818072 narecruitingnot on this mapstarted 2023, after this paper: background citation

The Prevalence, Risk Factors and Optimal Biopsy Protocol of Barrett's Esophagus in Taiwan - A Prospective Randomized Study

TypeinterventionalSponsorE-DA HospitalRan2023 to 2026Enrolled165ConditionsBarrett's Esophagus, Intestinal MetaplasiaArmsOne biopsy, Three biopsy, Seattle protocol, Endoscopy
3 · Its place in the literature

Who cites it

549 citing papers in PubMed, 16 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Cost effectiveness analysis of Barrett's esophagus screening: A systematic review.Best practice & research. Clinical gastroenterology · 2025
    Pooled it
  6. Quality indicators for upper GI endoscopy.Gastrointestinal endoscopy · 2025
    Guideline
  7. Pooled it
  8. Guideline
  9. Prevalence of Barrett's Esophagus and Esophageal Adenocarcinoma With and Without Gastroesophageal Reflux: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Pooled it
  10. Guideline
  11. Unsedated transnasal endoscopy for the detection of Barrett's esophagus: systematic review and meta-analysis.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023
    Pooled it
  12. AGA Clinical Practice Update on New Technology and Innovation for Surveillance and Screening in Barrett's Esophagus: Expert Review.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
    Guideline
  13. Pooled it
  14. Magnitude and Time-Trend Analysis of Postendoscopy Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
    Pooled it
  15. Pooled it
  16. Pooled it
  17. Trial
  18. Trial
  19. Trial
  20. Article

489 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Rebecca C FitzgeraldMRC Cancer Unit, University of Cambridge, Cambridge, UK.
Massimiliano di Pietro
Krish Ragunath
Yeng Ang
Jin-Yong Kang
Peter Watson
Nigel Trudgill
Praful Patel
Philip V Kaye
Scott Sanders
Maria O'Donovan
Elizabeth Bird-Lieberman
Pradeep Bhandari
Janusz A Jankowski
Stephen Attwood
Simon L Parsons
Duncan Loft
Jesper Lagergren
Paul Moayyedi
Georgios Lyratzopoulos
John de Caestecker
British Society of Gastroenterology

Funding

Cancer Research UK 4584Department of Health NIHR-RP-02-12-011Department of Health PDF-2011-04-047Medical Research Council MC_U105365007Medical Research Council MC_UU_12022/2
6 · The paper itself

Abstract

These guidelines provide a practical and evidence-based resource for the management of patients with Barrett's oesophagus and related early neoplasia. The Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument was followed to provide a methodological strategy for the guideline development. A systematic review of the literature was performed for English language articles published up until December 2012 in order to address controversial issues in Barrett's oesophagus including definition, screening and diagnosis, surveillance, pathological grading for dysplasia, management of dysplasia, and early cancer including training requirements. The rigour and quality of the studies was evaluated using the SIGN checklist system. Recommendations on each topic were scored by each author using a five-tier system (A+, strong agreement, to D+, strongly disagree). Statements that failed to reach substantial agreement among authors, defined as >80% agreement (A or A+), were revisited and modified until substantial agreement (>80%) was reached. In formulating these guidelines, we took into consideration benefits and risks for the population and national health system, as well as patient perspectives. For the first time, we have suggested stratification of patients according to their estimated cancer risk based on clinical and histopathological criteria. In order to improve communication between clinicians, we recommend the use of minimum datasets for reporting endoscopic and pathological findings. We advocate endoscopic therapy for high-grade dysplasia and early cancer, which should be performed in high-volume centres. We hope that these guidelines will standardise and improve management for patients with Barrett's oesophagus and related neoplasia.

Indexed as

Barrett EsophagusAblation TechniquesAdenocarcinomaBiopsyCost-Benefit AnalysisDecision Support TechniquesEarly Detection of CancerEsophageal NeoplasmsEsophagectomyEsophagoscopyEsophagusHumansRisk AssessmentRisk FactorsUnited KingdomUnited StatesBARRETT'S CARCINOMABARRETT'S METAPLASIABARRETT'S OESOPHAGUSGASTROESOPHAGEAL REFLUX DISEASEOESOPHAGEAL CANCER

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.