ArticleHuman vaccines & immunotherapeutics2014
Medical and economic burden of influenza in the elderly population in central and eastern European countries.
Article in Human vaccines & immunotherapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Costs and cost-effectiveness of influenza illness and vaccination in low- and middle-income countries: A systematic review from 2012 to 2022.PLoS medicine · 2024Pooled it
- Influenza as an important factor causing increased risk of patients' deaths, excessive morbidity and prolonged hospital stays.Archives of medical science : AMS · 2023Article
- Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly.Nature communications · 2022Article
- Unintended beneficial effects of COVID-19 on influenza-associated emergency department use in Korea.The American journal of emergency medicine · 2022Article
- Characterization and Outcomes of SARS-CoV-2 Infection in Overweight and Obese Patients: A Dynamic Comparison of COVID-19 Pandemic Waves.Journal of clinical medicine · 2022Article
- Seasonal Influenza and Low Flu Vaccination Coverage as Important Factors Modifying the Costs and Availability of Hospital Services in Poland: A Retrospective Comparative Study.International journal of environmental research and public health · 2021Article
- Review
- Flu Vaccinations in Pharmacies-A Review of Pharmacists Fighting Pandemics and Infectious Diseases.International journal of environmental research and public health · 2020Review
- Seasonal influenza vaccination among older adults in Jordan: prevalence, knowledge, and attitudes.Human vaccines & immunotherapeutics · 2020Article
- Burden of influenza in Romania. A retrospective analysis of 2014/15 - 2018/19 seasons in Romania.Germs · 2020Article
- Economic and operational impact of an improved pathway using rapid molecular diagnostic testing for patients with influenza-like illness in a German emergency department.Journal of clinical monitoring and computing · 2019Article
- The 2017-2018 influenza season in Bucharest, Romania: epidemiology and characteristics of hospital admissions for influenza-like illness.BMC infectious diseases · 2019Article
- Circulation of influenza A and B in the Czech Republic from 2000-2001 to 2015-2016.BMC infectious diseases · 2019Article
- Advances in measuring influenza burden of disease.Influenza and other respiratory viruses · 2018Article
- Estimating burden of influenza-associated influenza-like illness and severe acute respiratory infection at public healthcare facilities in Romania during the 2011/12-2015/16 influenza seasons.Influenza and other respiratory viruses · 2018Article
- Viral pathogens among elderly people with acute respiratory infections in Shanghai, China: Preliminary results from a laboratory-based surveillance, 2012-2015.Journal of medical virology · 2017Article
- The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe?Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2017Article
- Costs associated with influenza-related hospitalization in the elderly.Human vaccines & immunotherapeutics · 2017Article
- Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance.Influenza and other respiratory viruses · 2015Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Influenza affects 5-15% of the population during an epidemic. In Western Europe, vaccination of at-risk groups forms the cornerstone of influenza prevention. However, vaccination coverage of the elderly (> 65 y) is often low in Central and Eastern Europe (CEE); potentially because a paucity of country-specific data limits evidence-based policy making. Therefore the medical and economic burden of influenza were estimated in elderly populations in the Czech Republic, Hungary, Kazakhstan, Poland, Romania, and Ukraine. Data covering national influenza vaccination policies, surveillance and reporting, healthcare costs, populations, and epidemiology were obtained via literature review, open-access websites and databases, and interviews with experts. A simplified model of patient treatment flow incorporating cost, population, and incidence/prevalence data was used to calculate the influenza burden per country. In the elderly, influenza represented a large burden on the assessed healthcare systems, with yearly excess hospitalization rates of ~30/100,000. Burden varied between countries and was likely influenced by population size, surveillance system, healthcare provision, and vaccine coverage. The greatest burden was found in Poland, where direct costs were over EUR 5 million. Substantial differences in data availability and quality were identified, and to fully quantify the burden of influenza in CEE, influenza reporting systems should be standardized. This study most probably underestimates the real burden of influenza, however the public health problem is recognized worldwide, and will further increase with population aging. Extending influenza vaccination of the elderly may be a cost-effective way to reduce the burden of influenza in CEE.
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