ArticleNeurogastroenterology and motility2014
Novel MRI tests of orocecal transit time and whole gut transit time: studies in normal subjects.
Article in Neurogastroenterology and motility, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimising Measurement of Small and Large Bowel Transit During MRI Scanning and Characterising IBS Subtypes and Their Response to Stress Using MRI (Study 1)
MRI Assessment in Newly Diagnosed Coeliac Disease and Following Gluten-free Diet Treatment
Who cites it
29 citing papers in PubMed, 68 citations in OpenAlex.
- Gastrointestinal Transit Time Assessed Using a CT-Based Radiopaque Marker Method in Patients With Acute Pancreatitis During Methylnaltrexone Treatment.Neurogastroenterology and motility · 2025Trial
- Magnetic Resonance Imaging Reveals Novel Insights into the Dual Mode of Action of Bisacodyl: A Randomized, Placebo-controlled Trial in Constipation.Clinical pharmacology and therapeutics · 2025Trial
- Trial
- Mechanisms underlying effects of kiwifruit on intestinal function shown by MRI in healthy volunteers.Alimentary pharmacology & therapeutics · 2019Trial
- The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls.International journal of molecular sciences · 2019Trial
- Trial
- Colonic response to laxative ingestion as assessed by MRI differs in constipated irritable bowel syndrome compared to functional constipation.Neurogastroenterology and motility · 2016Trial
- In vivo comparison of enteric capsule shells composed of different HPMCAS grades after simultaneous intake by dual MRI labeling and pharmacokinetics.International journal of pharmaceutics: X · 2026Article
- Gastroparesis Phenotyping: Current Methods and Emerging Opportunities With Magnetic Resonance Imaging.Neurogastroenterology and motility · 2026Review
- Evaluation of pan-alimentary MRI examinations: intrasubject variability and examination duration.Abdominal radiology (New York) · 2026Article
- Radiopaque intestinal contents due to simultaneous ingestion of lanthanum carbonate and sodium zirconium cyclosilicate: a nephrology image.Journal of nephrology · 2025Article
- An ingestible device for automated sampling and location tracing in gastrointestinal tract.PloS one · 2025Article
- Pan-Alimentary Magnetic Resonance Imaging of Severe Gastroparesis May Facilitate Diagnosis and Treatment.Clinical case reports · 2024Article
- Enteric-Coated Capsules Providing Reliable Site-Specific Drug Delivery to the Distal Ileum.Molecular pharmaceutics · 2024Article
- Article
- Feasibility Study of a New Magnetic Resonance Imaging Mini-capsule Device to Measure Whole Gut Transit Time in Paediatric Constipation.Journal of pediatric gastroenterology and nutrition · 2020Article
- Structural features of bovine colostral immunoglobulin that confer proteolytic stability in a simulated intestinal fluid.The Journal of biological chemistry · 2020Article
- Imaging Measurement of Whole Gut Transit Time in Paediatric and Adult Functional Gastrointestinal Disorders: A Systematic Review and Narrative Synthesis.Diagnostics (Basel, Switzerland) · 2019Review
- MRI of the Colon in the Pharmaceutical Field: The Future before us.Pharmaceutics · 2019Review
- Will MRI of gastrointestinal function parallel the clinical success of cine cardiac MRI?The British journal of radiology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundColonic transit tests are used to manage patients with Functional Gastrointestinal Disorders. Some tests used expose patients to ionizing radiation. The aim of this study was to compare novel magnetic resonance imaging (MRI) tests for measuring orocecal transit time (OCTT) and whole gut transit time (WGT), which also provide data on colonic volumes.
methods21 healthy volunteers participated. Study 1: OCTT was determined from the arrival of the head of a meal into the cecum using MRI and the Lactose Ureide breath test (LUBT), performed concurrently. Study 2: WGT was assessed using novel MRI marker capsules and radio-opaque markers (ROMs), taken on the same morning. Studies were repeated 1 week later. KEY
resultsOCTT measured using MRI and LUBT was 225 min (IQR 180-270) and 225 min (IQR 165-278), respectively, correlation r(s) = 0.28 (ns). WGT measured using MRI marker capsules and ROMs was 28 h (IQR 4-50) and 31 h ± 3 (SEM), respectively, correlation r(s) = 0.85 (p < 0.0001). Repeatability assessed using the intraclass correlation coefficient (ICC) was 0.45 (p = 0.017) and 0.35 (p = 0.058) for MRI and LUBT OCTT tests. Better repeatability was observed for the WGT tests, ICC being 0.61 for the MRI marker capsules (p = 0.001) and 0.69 for the ROM method (p < 0.001) respectively. CONCLUSIONS & INFERENCES: The MRI WGT method is simple, convenient, does not use X-ray and compares well with the widely used ROM method. Both OCTT measurements showed modest reproducibility and the MRI method showed modest inter-observer agreement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.