ArticleBMC oral health2013
Periodontal conditions in patients with Marfan syndrome - a multicenter case control study.
Article in BMC oral health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Oral Health Status in Marfan Syndrome: A Systematic Review and Meta-Analysis of 353 Cases.International journal of environmental research and public health · 2022Pooled it
- Association between Marfan syndrome and oral health status: A systematic review and meta-analysis.Medicina oral, patologia oral y cirugia bucal · 2019Pooled it
- Impact of rare diseases in oral health.Medicina oral, patologia oral y cirugia bucal · 2016Pooled it
- Oral health and oral health-related quality of life in people with Marfan syndrome: a cross-sectional study.BMC oral health · 2025Article
- Review
- Temporomandibular disorders in individuals with Marfan syndrome: an exploratory analysis.Head & face medicine · 2024Article
- A case series describing the risk of periodontal disease in Marfan syndrome patients harboring a possible aortic aneurysm or dissection.BMC oral health · 2022Article
- Prevalence of Periodontitis among Patients Diagnosed with Marfan Syndrome: A Cross-Sectional Study Comparing Samples of Healthy Patients.BioMed research international · 2022Article
- Mouse Model of Loeys-Dietz Syndrome Shows Elevated Susceptibility to Periodontitis via Alterations in Transforming Growth Factor-Beta Signaling.Frontiers in physiology · 2021Article
- Article
- Oral Health-Related Quality of Life in People with Rare Hereditary Connective Tissue Disorders: Marfan Syndrome.International journal of environmental research and public health · 2018Article
- Dental findings in marfan syndrome: a case report.Journal of Istanbul University Faculty of Dentistry · 2017Article
- The role of the multidisciplinary health care team in the management of patients with Marfan syndrome.Journal of multidisciplinary healthcare · 2016Review
- Marfan Syndrome: oral implication and management.ORAL & implantologyReview
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMarfan syndrome (MFS) is a disorder of the connective tissues. Alterations of the elastic fibers may manifest in different tissues especially in the skeletal, cardiovascular and ocular system. Oral manifestations like orthodontic or skeletal anomalies and fragility of the temporomandibular joint have been well described by various authors. However, no data are available regarding a possible periodontal involvement of MFS. Hence, the aim of the present study was to investigate for the first time if MFS may increase the susceptibility to periodontitis.
methodsA comprehensive periodontal examination including documentation of probing pocket depth, gingival recession, clinical attachment level, and bleeding on probing was conducted in all patients. In addition, dental conditions were assessed by determining the Index for Decayed, Missing and Filled Teeth (DMFT) and a self-administered questionnaire was filled out by patients. For statistical analysis, the unpaired t-Test was applied (level of significance: p < 0.05). Both groups were matched concerning well known periodontal risk factors like age, gender and smoking habits.
results82 participants, 51 patients with MFS (30 female and 21 male, mean age: 40.20 ± 15.35 years) and 31 sound controls (17 female and 14 male, mean age: 40.29 ± 13.94 years), were examined. All assessed periodontal and dental parameters were not significantly different between groups.
conclusionsBased on our data, patients with MFS did not reveal a higher prevalence of periodontitis compared to the control group. However, Marfan patients showed a tendency to more inflammation signs, which can be explained by the crowded teeth. Therefore, a regular professional cleaning of the teeth is recommendable (i.e., 6 months intervals) in order to reduce the bacterial biofilm in the oral cavity and thus resulting in a decreased risk of systemic diseases, specifically endocarditis.
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