Trial reportThe British journal of nutrition2014
Effects on obese women of the sugar sucrose added to the diet over 28 d: a quasi-randomised, single-blind, controlled trial.
Trial report in The British journal of nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Health Effects of Sugar-Sweetened and Artificially Sweetened Beverages: Umbrella Review and Evidence-Based Consensus Statement of the Korean Diabetes Association and the Korean Nutrition Society.Diabetes & metabolism journal · 2026Pooled it
- The effects of non-nutritive sweeteners on energy and macronutrients intake in adults: a grade-assessed systematic review and meta-analyses of randomized controlled trials.Frontiers in nutrition · 2024Pooled it
- Association of Low- and No-Calorie Sweetened Beverages as a Replacement for Sugar-Sweetened Beverages With Body Weight and Cardiometabolic Risk: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- High versus low-added sugar consumption for the primary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2022Pooled it
- The effects of low-calorie sweeteners on energy intake and body weight: a systematic review and meta-analyses of sustained intervention studies.International journal of obesity (2005) · 2021Pooled it
- Environmental interventions to reduce the consumption of sugar-sweetened beverages and their effects on health.The Cochrane database of systematic reviews · 2019Pooled it
- Association between intake of non-sugar sweeteners and health outcomes: systematic review and meta-analyses of randomised and non-randomised controlled trials and observational studies.BMJ (Clinical research ed.) · 2019Pooled it
- Effects of dietary recommendations for reducing free sugar intakes, on free sugar intakes, dietary profiles and anthropometry: a randomised controlled trial.The British journal of nutrition · 2025Trial
- The effects of the form of sugar (solid vs. beverage) on body weight and fMRI activation: A randomized controlled pilot study.PloS one · 2021Trial
- Energy compensation following consumption of sugar-reduced products: a randomized controlled trial.European journal of nutrition · 2016Trial
- Protocol: The effects of nutrient- vs food- vs food-substitution-based dietary recommendations for reducing free sugar intakes, on free sugar intakes, dietary profiles and sweet taste outcomes: A randomised controlled trial.Nutrition and health · 2024Article
- Low-energy sweeteners and body weight: a citation network analysis.BMJ nutrition, prevention & health · 2021Review
- Soft drink intake is associated with weight gain, regardless of physical activity levels: the health workers cohort study.The international journal of behavioral nutrition and physical activity · 2020Article
- Article
- Review
- Changes in Sugar-Sweetened Soda Consumption, Weight, and Waist Circumference: 2-Year Cohort of Mexican Women.American journal of public health · 2017Article
- Misconceptions about fructose-containing sugars and their role in the obesity epidemic.Nutrition research reviews · 2014Article
- Liquid calories, energy compensation and weight: what we know and what we still need to learn.The British journal of nutrition · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
To investigate whether obese women can compensate for sucrose added to the diet when it is given blind, rather than gaining weight or exhibiting dysfunctional regulation of intake, in the present study, forty-one healthy obese (BMI 30-35 kg/m²) women (age 20-50 years), not currently dieting, were randomly assigned to consume sucrose (n 20) or aspartame (n 21) drinks over 4 weeks in a parallel single-blind design. Over the 4 weeks, one group consumed 4 × 250 ml sucrose drinks (total 1800 kJ/d) and the other group consumed 4 × 250 ml aspartame drinks. During the baseline week and experimental weeks, body weight and other biometric data were measured and steps per day, food intake using 7 d unweighed food diaries, and mood using ten- or seven-point Likert scales four times a day were recorded. At the end of the experiment, the participants weighed 1·72 (SE 0·47) kg less than the value predicted by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) model; the predicted body weight accounted for 94·3% of the variance in the observed body weight and experimental group accounted for a further 1·1% of the variance in the observed body weight, showing that women consuming sucrose drinks gained significantly less weight than predicted. The reported daily energy intake did not increase significantly, and sucrose supplements significantly reduced the reported voluntary sugar, starch and fat intake compared with aspartame. There were no effects on appetite or mood. Over 4 weeks, as part of everyday eating, sucrose given blind in soft drinks was partially compensated for by obese women, as in previous experiments with healthy and overweight participants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.