ArticleBMC plant biology2013
CYP709B3, a cytochrome P450 monooxygenase gene involved in salt tolerance in Arabidopsis thaliana.
Article in BMC plant biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
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64 citing papers in PubMed, 166 citations in OpenAlex.
- Genome-wide characterization of cytochrome P450 genes in Solanum tuberosum and StCYP481 role in salt tolerance.BMC plant biology · 2026Article
- Pan-genome analysis reveals structural variation- associated expression and evolutionary diversity of theFrontiers in plant science · 2026Article
- Comparative genomics and evolutionary insights in divergence and expression of CYP450 super gene family in citrus (C. sinensis, C. grandis&P. trifoliata).BMC plant biology · 2025Article
- GWAS and gene co-expression network analysis reveal the genetic control of seed germination under salt stress in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Adaptive Strategies to Biotic Stress in Qatar's Native Flora.Life (Basel, Switzerland) · 2025Review
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- Genome-wide characterization of the cytochrome P450 gene family in Solanum melongena and functional analysis of SmCYP82C1 under cold stress.BMC plant biology · 2025Article
- The combination of linkage mapping, genome-wide association study, and dynamic transcriptome analysis reveals conserved candidate genes for salt tolerance in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- GWAS and transcriptome analyses unravel ZmGRAS15 regulates drought tolerance and root elongation in maize.BMC genomics · 2025Article
- OsFKBP12 transduces the sucrose signal from OsNIN8 to the OsTOR pathway in a loosely binding manner for cell division.iScience · 2025Article
- Characterization of theInternational journal of molecular sciences · 2024Article
- Weighted gene co-expression network analysis reveals hub genes regulating response to salt stress in peanut.BMC plant biology · 2024Article
- Physiological and Molecular Responses ofPlants (Basel, Switzerland) · 2024Article
- Comparative transcriptomic and proteomic analyses of two salt-tolerant alfalfa (Frontiers in plant science · 2024Article
- Genome-wide analysis of theFrontiers in plant science · 2024Article
- Cytochrome P450 Gene Families: Role in Plant Secondary Metabolites Production and Plant Defense.Journal of xenobiotics · 2023Review
- Genome-Wide Identification and Expression Profiling of Cytochrome P450 Monooxygenase Superfamily in Foxtail Millet.International journal of molecular sciences · 2023Article
- Role of Cytochrome P450 Enzyme in Plant Microorganisms' Communication: A Focus on Grapevine.International journal of molecular sciences · 2023Review
- Article
- Insights into the Cytochrome P450 Monooxygenase Superfamily inInternational journal of molecular sciences · 2022Article
4 more citing papers are in PubMed but not listed here.
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4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWithin the Arabidopsis genome, there are 272 cytochrome P450 monooxygenase (P450) genes. However, the biological functions of the majority of these P450s remain unknown. The CYP709B family of P450s includes three gene members, CYP709B1, CYP709B2 and CYP709B3, which have high amino acid sequence similarity and lack reports elucidating biological functions.
resultsWe identified T-DNA insertion-based null mutants of the CYP709B subfamily of genes. No obvious morphological phenotypes were exhibited under normal growth conditions. When the responses to ABA and salt stress were studied in these mutants, only the cyp709b3 mutant showed sensitivity to ABA and salt during germination. Under moderate salt treatment (150 mM NaCl), cyp709b3 showed a higher percentage of damaged seedlings, indicating a lower tolerance to salt stress. CYP709B3 was highly expressed in all analyzed tissues and especially high in seedlings and leaves. In contrast, CYP709B1 and CYP709B2 were highly expressed in siliques, but were at very low levels in other tissues. Under salt stress condition, CYP709B3 gene expression was induced after 24 hr and remained at high expression level. Expression of the wild type CYP709B3 gene in the cyp709b3 mutant fully complemented the salt intolerant phenotype. Furthermore, metabolite profiling analysis revealed some differences between wild type and cyp709b3 mutant plants, supporting the salt intolerance phenotype of the cyp709b3 mutant.
conclusionsThese results suggest that CYP709B3 plays a role in ABA and salt stress response and provides evidence to support the functions of cytochrome P450 enzymes in plant stress response.
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