Evidence map›Paper›PMID 24163789›Full record

ArticleOptical nanoscopy2012

SOFI-based 3D superresolution sectioning with a widefield microscope.

Thomas Dertinger, Jianmin Xu, Omeed Foroutan Naini, Robert Vogel, Shimon Weiss

Abstract read
In one paragraph

Article in Optical nanoscopy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Cryo-SOFI enabling low-dose super-resolution correlative light and electron cryo-microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  9. Article
  10. Review
  11. Article
  12. Labeling Cytosolic Targets in Live Cells with Blinking Probes.The journal of physical chemistry letters · 2013
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas DertingerDepartment of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, CA, USA ; SOFast GmbH, Dresdener Str 14, 10999 Berlin, Germany.
Jianmin Xu
Omeed Foroutan Naini
Robert Vogel
Shimon Weiss

Funding

New Probe and Methods for Correlated LM & EMR01GM086197 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ADAMS, STEPHEN ROY, BOASSA, DANIELA · 2008 to 2020
$8.3M
Multimodal Qdot Probes for Bioimaging of Cells and Tumors in Small AnimalsR01EB000312 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WEISS, SHIMON · 2002 to 2010
$7.5M
NIBIB NIH HHS R01 EB000312NIGMS NIH HHS R01 GM086197
6 · The paper itself

Abstract

backgroundFluorescence-based biological imaging has been revolutionized by the recent introduction of superresolution microscopy methods. 3D superresolution microscopy, however, remains a challenge as its implementation by existing superresolution methods is non-trivial.

methodsHere we demonstrate a facile and straightforward 3D superresolution imaging and sectioning of the cytoskeletal network of a fixed cell using superresolution optical fluctuation imaging (SOFI) performed on a conventional lamp-based widefield microscope. RESULTS AND

conclusionSOFI's inherent sectioning capability effectively transforms a conventional widefield microscope into a superresolution 'confocal widefield' microscope.

Identifiers

PMID24163789
PMCPMC3807127

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.