ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2012
Large Fluorescence Enhancements of Fluorophore Ensembles with Multilayer Plasmonic Substrates: Comparison of Theory and Experimental Results.
Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- Emerging Strategies in Enhancing Singlet Oxygen Generation of Nano-Photosensitizers Toward Advanced Phototherapy.Nano-micro letters · 2022Review
- Imaging optical fields below metal films and metal-dielectric waveguides by a scanning microscope.Journal of applied physics · 2017Article
- Dye-Labeled Polyacryloyl Hydrazide-Ag Nanoparticle Fluorescent Probe for Ultrasensitive and Selective Detection of Au Ion.ACS omega · 2017Article
- Several hundred-fold enhanced fluorescence from single fluorophores assembled on silver nanoparticle-dielectric-metal substrate.Chemical communications (Cambridge, England) · 2015Article
- Selectable Surface and Bulk Fluorescence Imaging with Plasmon-Coupled Waveguides.The journal of physical chemistry. C, Nanomaterials and interfaces · 2015Article
- Fluorescence Spectroscopy with Metal-Dielectric Waveguides.The journal of physical chemistry. C, Nanomaterials and interfaces · 2015Article
- Binding of fusion protein FLSC IgG1 to CCR5 is enhanced by CCR5 antagonist Maraviroc.Antiviral research · 2014Article
- Tamm State-Coupled Emission: Effect of Probe Location and Emission Wavelength.The journal of physical chemistry. C, Nanomaterials and interfaces · 2014Article
- Imaging of Protein Secretion from a Single Cell Using Plasmonic Substrates.BioNanoScience · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Multilayer substrates consisting of a glass slide, silver mirror, silica layer, and silver nanoparticles were fabricated using magnetron sputtering. This new geometry of substrates with backplane mirror and dielectric photonic cavity produced large average fluorescence enhancements up to 190-fold. Fluorescence enhancements of five fluorescent probes were measured over the broad spectral range from 470 to 800 nm. Fluorescent probes were streptavidin conjugates attached to the substrate surface through a layer of biotinylated bovine serum albumin. The protein layers represent a common surface modification for surface-based bioassays such as immunoassays or molecular diagnostic assays. We found that optimal enhancement is dependent on the thickness of the dielectric layer separating the silver mirror and the silver nanoparticles and on the spectral range. We performed numerical calculations for enhancement in both the excitation and emission using finite element method (FEM) the results of which were in qualitative agreement with the experimental results. The described method for fabrication multilayered substrates and the results obtained with protein layers demonstrate great potential for the design of simple and ultrasensitive fluorometric bioassays with large optical amplifications compared to the standard approaches of enzyme-based bioassays with dielectric surfaces.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.