ArticleCase reports in oncology2013
Malignant Transformation from Endometriosis to Atypical Endometriosis and Finally to Endometrioid Adenocarcinoma within 10 Years.
Article in Case reports in oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 38 citations in OpenAlex.
- From Inflammation to Malignancy: The Link Between Endometriosis and Gynecological Cancers.International journal of molecular sciences · 2025Review
- Anatomic subtype-specific causal effects of endometriosis on ovarian cancer: a two-sample Mendelian randomization study.Discover oncology · 2025Article
- Genetic Links between Endometriosis and Endometriosis-Associated Ovarian Cancer-A Narrative Review (Endometriosis-Associated Cancer).Life (Basel, Switzerland) · 2024Review
- Endometriosis-Related Ovarian Cancer: Where Are We Now? A Narrative Review towards a Pragmatic Approach.Journal of clinical medicine · 2024Review
- Endometrial cancer with concomitant endometriosis is highly associated with ovarian endometrioid carcinoma: a retrospective cohort study.BMC women's health · 2022Article
- Predictive factors of endometriosis progression into ovarian cancer.Journal of ovarian research · 2022Article
- The many faces of endometriosis.Autopsy & case reports · 2022Article
- Ectopic Endometrium: The Pathologist's Perspective.International journal of molecular sciences · 2021Review
- Clinical and Pathological Significance of Cellular Atypia in Endometriosis.Medicina (Kaunas, Lithuania) · 2021Article
- A 24 year-old patient with no prior history of endometriosis diagnosed with bilateral ovarian endometrioid adenocarcinoma arising in endometriosis.Gynecologic oncology reports · 2021Article
- Poorly differentiated mucinous carcinoma with signet ring cells in an ovarian endometriotic cyst: a case report.Diagnostic pathology · 2019Article
- Genes' Interactions: A Major Contributor to the Malignant Transformation of Endometriosis.International journal of molecular sciences · 2019Review
- Morphological and immunohistochemical characterization of spontaneous endometriosis in rhesus macaques (Primate biology · 2017Article
- Cyst fluid hemoglobin species in endometriosis and its malignant transformation: The role of metallobiology.Oncology letters · 2016Article
- The Association between Endometriomas and Ovarian Cancer: Preventive Effect of Inhibiting Ovulation and Menstruation during Reproductive Life.BioMed research international · 2015Review
- Long-Term Follow-Up after Surgical Management for Atypical Endometriosis: A Series of Nine Cases.Case reports in oncologyArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atypical endometriosis is reported to possess a precancerous potential attributed to premalignant changes characterized by cytological atypia and architecture proliferation. Moreover, the coexistence of atypical endometriosis and neoplasms had been reported. However, cases of atypical endometriosis transformation to carcinoma are rarely reported. We describe the case of a 33-year-old woman who had a long therapeutic history of endometriosis. Three laparoscopic surgeries were performed to treat endometriosis. After the third surgery, she was diagnosed as having grade 1 endometrioid adenocarcinoma. The histological review of the previous surgery confirmed the diagnosis of atypical endometriosis based on the second specimen. The patient's disease progressed from a benign endometriotic cyst to atypical endometriosis and finally to endometrioid adenocarcinoma within 10 years. When we encounter cases of atypical endometriosis, it is necessary to consider the possibility of ovarian cancer and carefully follow the patients for long periods.
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