ArticleIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society2012
Polarized Enhanced Backscattering Spectroscopy for Characterization of Biological Tissues at Subdiffusion Length-scales.
Article in IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 28 citations in OpenAlex.
- Polarization-based smoke removal method for surgical images.Biomedical optics express · 2022Article
- Optical anisotropy measurement in normal and cancerous tissues: backscattering technique.Biomedical optics express · 2020Article
- Platform for quantitative multiscale imaging of tissue composition.Biomedical optics express · 2020Article
- Fully automated fiber-based optical spectroscopy system for use in a clinical setting.Journal of biomedical optics · 2018Article
- The transformation of the nuclear nanoarchitecture in human field carcinogenesis.Future science OA · 2017Review
- Rectal Optical Markers for In Vivo Risk Stratification of Premalignant Colorectal Lesions.Clinical cancer research : an official journal of the American Association for Cancer Research · 2015Article
- In vivo risk analysis of pancreatic cancer through optical characterization of duodenal mucosa.Pancreas · 2015Article
- Subdiffusion reflectance spectroscopy to measure tissue ultrastructure and microvasculature: model and inverse algorithm.Journal of biomedical optics · 2015Article
- Nanoscale changes in chromatin organization represent the initial steps of tumorigenesis: a transmission electron microscopy study.BMC cancer · 2014Article
- Buccal spectral markers for lung cancer risk stratification.PloS one · 2014Article
- Ultrastructural alterations in field carcinogenesis measured by enhanced backscattering spectroscopy.Journal of biomedical optics · 2013Article
- Advances in biophotonics detection of field carcinogenesis for colon cancer risk stratification.Journal of Cancer · 2013Article
- Analytical light reflectance models for overlapping illumination and collection area geometries.Applied optics · 2012Article
- Open source software for electric field Monte Carlo simulation of coherent backscattering in biological media containing birefringence.Journal of biomedical optics · 2012Article
- A fiber optic probe design to measure depth-limited optical properties in-vivo with low-coherence enhanced backscattering (LEBS) spectroscopy.Optics express · 2012Article
- Monte Carlo model of the penetration depth for polarization gating spectroscopy: influence of illumination-collection geometry and sample optical properties.Applied optics · 2012Article
- Measurement of the spatial backscattering impulse-response at short length scales with polarized enhanced backscattering.Optics letters · 2011Article
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Authors and funding
7 authors at 2 institutions in 1 country.
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Abstract
Since the early 1980's, the enhanced backscattering (EBS) phenomenon has been well-studied in a large variety of non-biological materials. Yet, until recently the use of conventional EBS for the characterization of biological tissue has been fairly limited. In this work we detail the unique ability of EBS to provide spectroscopic, polarimetric, and depth-resolved characterization of biological tissue using a simple backscattering instrument. We first explain the experimental and numerical procedures used to accurately measure and model the full azimuthal EBS peak shape in biological tissue. Next we explore the peak shape and height dependencies for different polarization channels and spatial coherence of illumination. We then illustrate the extraordinary sensitivity of EBS to the shape of the scattering phase function using suspensions of latex microspheres. Finally, we apply EBS to biological tissue samples in order to measure optical properties and observe the spatial length-scales at which backscattering is altered in early colon carcinogenesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.