ArticleNational journal of maxillofacial surgery2013
Osteogenic potential of cissus qudrangularis assessed with osteopontin expression.
Article in National journal of maxillofacial surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Evaluation of osteogenic potential of Cissus quadrangularis on mandibular alveolar ridge distraction.BMC oral health · 2021Trial
- Exploring the Role ofOrthopedic research and reviews · 2026Review
- Article
- Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-label Control Trial.Craniomaxillofacial trauma & reconstruction · 2023Article
- Biocompatibility and antioxidant activity of a novel carrageenan based injectable hydrogel scaffold incorporated with Cissus quadrangularis: an in vitro study.BMC oral health · 2022Article
- Chitosan/Gold Hybrid Nanoparticles Enriched Electrospun PVA Nanofibrous Mats for the Topical Delivery ofInternational journal of nanomedicine · 2021Article
- An Assessment of the Osteogenic Potential ofJournal of maxillofacial and oral surgery · 2020Article
- A short review on pharmacological activity of Cissus quadrangularis.Bioinformation · 2020Article
- Osteogenic potential of hexane and dichloromethane fraction of Cissus quadrangularis on murine preosteoblast cell line MC3T3-E1 (subclone 4).Journal of cellular physiology · 2019Article
- Herbal remedies for mandibular fracture healing.National journal of maxillofacial surgery · 2014Article
- Zebrafish caudal fin model to investigate the role of Cissus quadrangularis, bioceramics, and tendon extracellular matrix scaffolds in bone regeneration.Journal of oral biology and craniofacial researchArticle
- Medicinal plants and bone healing.National journal of maxillofacial surgeryReview
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFracture healing involves complex processes of cell and tissue proliferation and differentiation. Many factors are involved, including growth factors, inflammatory cytokines, antioxidants, bone breakdown (osteoclast) and bone building (osteoblast) cells, hormones, amino acids, and uncounted nutrients. We studied the osteogenic potential of Cissus quadrangularis (CQ), a plant that has been customarily used in the Indian subcontinent to hasten the process of healing in bone fractures. MATERIALS AND
methodsTotal of 60 patients (age, 20-35 years) of mandible fracture was divided in two groups. Patients of group 1 were given capsules of CQ and fracture healing was assessed with osteopontin expression during treatment. Group 2 was control group.
resultsClinical and radiological analysis in our study was suggestive of better healing of fractures in group 1. All the samples of group 1 examined for osteopontin expression using western blot analysis and flow cytometry showed significant levels of expression of osteopontin protein and CD4+ T cells expressing osteopontin, respectively.
conclusionWe conclude that CQ accelerates fracture healing and also causes early remodeling of fracture callus.
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