ArticleJournal of experimental botany2013
Rice DEP1, encoding a highly cysteine-rich G protein γ subunit, confers cadmium tolerance on yeast cells and plants.
Article in Journal of experimental botany, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- The heterotrimeric G protein γ3 subunit, RGG3/GS3, integrates sugar-starvation and hormone-responsive signaling pathways to promote coleoptile elongation during anaerobic germination in rice.Plant molecular biology · 2025Article
- Novel repetitive elements in plant-specific tails of Gγ proteins as the functional unit in G-protein signaling in crops.The Plant cell · 2025Article
- The involvement of cyclotides in the heavy metal tolerance of Viola spp.Scientific reports · 2024Article
- Agronomic potential of plant-specific Gγ proteins.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- Rapid Visual Detection of Elite Erect PanicleCurrent issues in molecular biology · 2024Article
- Fine Mapping and Candidate Gene Analysis of Rice Grain Length QTLInternational journal of molecular sciences · 2023Article
- RNA-Seq Transcriptome Analysis and Evolution ofInternational journal of molecular sciences · 2023Article
- Heterotrimeric G Protein Signaling in Abiotic Stress.Plants (Basel, Switzerland) · 2022Review
- Review
- TT2 controls rice thermotolerance through SCT1-dependent alteration of wax biosynthesis.Nature plants · 2022Article
- Molecular Insights into Inflorescence Meristem Specification for Yield Potential in Cereal Crops.International journal of molecular sciences · 2021Review
- Genetic Control Diversity Drives Differences Between Cadmium Distribution and Tolerance in Rice.Frontiers in plant science · 2021Article
- Transcription Factor GmWRKY142 Confers Cadmium Resistance by Up-Regulating the Cadmium Tolerance 1-Like Genes.Frontiers in plant science · 2020Article
- Cloning, characterization of TaGS3 and identification of allelic variation associated with kernel traits in wheat (Triticum aestivum L.).BMC genetics · 2019Article
- Review
- Dissecting the Genetic Basis of Grain Size and Weight in Barley (Frontiers in plant science · 2019Article
- Comprehensive Analysis of the Cadmium Tolerance of Abscisic Acid-, Stress- and Ripening-Induced Proteins (ASRs) in Maize.International journal of molecular sciences · 2019Article
- Characterization of Heterotrimeric G Protein γ4 Subunit in Rice.International journal of molecular sciences · 2018Article
- Comparative analysis of Cd-responsive maize and rice transcriptomes highlights Cd co-modulated orthologs.BMC genomics · 2018Article
- Duplicated RGS (Regulator of G-protein signaling) proteins exhibit conserved biochemical but differential transcriptional regulation of heterotrimeric G-protein signaling in Brassica species.Scientific reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A rice cDNA, OsDEP1, encoding a highly cysteine (Cys)-rich G protein γ subunit, was initially identified as it conferred cadmium (Cd) tolerance on yeast cells. Of the 426 aa constituting OsDEP1, 120 are Cys residues (28.2%), of which 88 are clustered in the C-terminal half region (aa 170-426). To evaluate the independent effects of these two regions, two truncated versions of the OsDEP1-expressing plasmids pOsDEP1(1-169) and pOsDEP1(170-426) were used to examine their effects on yeast Cd tolerance. Although OsDEP1(170-426) conferred a similar level of Cd tolerance as the intact OsDEP1, OsDEP1(1-169) provided no such tolerance, indicating that the tolerance effect is localized to the aa 170-426 C-terminal peptide region. The Cd responses of transgenic Arabidopsis plants constitutively expressing OsDEP1, OsDEP1(1-169) or OsDEP1(170-426), were similar to the observations in yeast cells, with OsDEP1 and OsDEP1(170-426) transgenic plants displaying Cd tolerance but OsDEP1(1-169) plants showing no such tolerance. In addition, a positive correlation between the transcript levels of OsDEP1 or OsDEP1(170-426) in the transgenics and the Cd content of these plants upon Cd application was observed. As several Arabidopsis loss-of-function heterotrimeric G protein β and γ subunit gene mutants did not show differences in their Cd sensitivity compared with wild-type plants, we propose that the Cys-rich region of OsDEP1 may function directly as a trap for Cd ions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.