Evidence map›Paper›PMID 24163384›Full record

ArticlePsychosomatic medicine

Socioeconomic indices as independent correlates of C-reactive protein in the National Longitudinal Study of Adolescent Health.

Beverly H Brummett, Michael A Babyak, Abanish Singh, Rong Jiang, Redford B Williams, Kathleen Mullan Harris, Ilene C Siegler

Open access · greenAbstract read
In one paragraph

Article in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. A Call to Integrate Measures of Environmental Context into Research on Maternal Brain Health.International journal of environmental research and public health · 2025
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  19. Stressful life events, sexual orientation, and cardiometabolic risk among young adults in the United States.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2014
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Beverly H BrummettDuke University Medical Center, Box 2969, Durham, NC 27710. brummett@duke.edu.
Michael A Babyak
Abanish Singh
Rong Jiang
Redford B Williams
Kathleen Mullan Harris
Ilene C Siegler
Duke University Hospital · US

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
The Genetics Of Biobehavioral Risk Factors For CVDP01HL036587 · NHLBI · DUKE UNIVERSITY · PI KRAUS, WILLIAM E · 1986 to 2020
$35.9M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
NHLBI NIH HHS P01 HL036587NHLBI NIH HHS P01 HL36587NICHD NIH HHS P01 HD031921NICHD NIH HHS P01-HD31921NICHD NIH HHS R24 HD050924
6 · The paper itself

Abstract

objectivesTo examine the association between socioeconomic status (SES) and C-reactive protein (CRP) to understand how SES may increase the risk of cardiovascular disease and thus identify targets for prevention measures.

methodsPath models were used to examine direct and indirect associations of four indices of SES (objective early life built environment ratings, parental and participant education, and income) with CRP measured during early adulthood using data from the National Longitudinal Adolescent Health Study (n = 11,371; mean age = 29 years, range = 24-32 years; 53.8% women, 28.0% black participants). The present study examined potential mediation of the association of SES with CRP by way of body mass index (BMI), smoking, and alcohol consumption within white and black men and women.

resultsBMI was a mediator of the relation between parent education and CRP for white men (path coefficient [γ] = -0.05, p < .001) and women (γ = -0.05, p < .001). Smoking mediated the income-CRP (γ = -0.01, p < .01) and the education-CRP (γ = -0.07, p < .001) relation for white men. BMI mediated the relation between all measures of SES and CRP for white women (γ values between -0.02 and -0.05; p values < .01). None of the risk factors mediated the SES-CRP relation in black participants.

conclusionsThese findings indicate that the association of SES with CRP is influenced by both the timing and type of SES measure examined. In addition, race and sex play a role in how potential mediators are involved with the SES-CRP relationship, such that BMI and smoking were mediators in white men, whereas BMI was the sole mediator in white women.

Indexed as

Models, StatisticalAdolescentAdultAlcohol DrinkingBlack or African AmericanBody Mass IndexCardiovascular DiseasesC-Reactive ProteinFemaleHumansMaleNational Longitudinal Study of Adolescent HealthRisk FactorsSex DistributionSmokingSocial Determinants of HealthC-Reactive Proteinadd healthC-reactive proteinracesexsocioeconomic status

Identifiers

PMID24163384
PMCPMC3950330
OpenAlexW2327401228

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.