Evidence map›Paper›PMID 24163344›Full record

ArticleJournal of bacteriology2014

Liberate and grab it, ingest and digest it: the GbdR regulon of the pathogen Pseudomonas aeruginosa.

Erhard Bremer

Open access · bronzeAbstract readComment
In one paragraph

Article in Journal of bacteriology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Transcriptional Regulators Controlling Virulence inInternational journal of molecular sciences · 2023
    Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Erhard BremerPhilipps-University Marburg, Department of Biology, Laboratory for Microbiology, Marburg, Germany, and LOEWE-Center for Synthetic Microbiology, Philipps-University Marburg, Marburg, Germany.
Philipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The compatible solute glycine betaine is a powerful osmostress protectant, but many microorganisms can also use it as a nutrient. K. J. Hampel et al. (J. Bacteriol. 196:7-15, 2014) defined a regulon in the notorious pathogen Pseudomonas aeruginosa that comprises modules for the harvest and import of the glycine betaine biosynthetic precursor choline and its subsequent catabolism to pyruvate. The reported data link the GbdR activator with the metabolism of host-derived compounds (e.g., phosphocholine) and virulence traits of P. aeruginosa.

Indexed as

Gene Expression Regulation, BacterialRegulonPseudomonas aeruginosaTranscription FactorsTranscription Factors

Identifiers

PMID24163344
PMCPMC3911135
OpenAlexW2120514690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.