Evidence map›Paper›PMID 24163188›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2014

The psychosocial context impacts medication adherence after acute coronary syndrome.

Ian M Kronish, Nina Rieckmann, Matthew M Burg, Carmela Alcántara, Karina W Davidson

Abstract read
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ian M KronishCenter for Behavioral Cardiovascular Health, Columbia University Medical Center, PH9-311, 622 W168th Street, New York, NY, 10032, USA, ik2293@columbia.edu.
Nina Rieckmann
Matthew M Burg
Carmela Alcántara
Karina W Davidson

Funding

Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Depression, Biobehavioral Mechanisms, & CHD/Mortality OutcomesP01HL088117 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W. · 2008 to 2013
$12.5M
Ecological Link of Psychosocial Stress to Exercise: Personalized PathwaysR01HL115941 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BURG, MATTHEW M, DAVIDSON, KARINA W. · 2012 to 2014
$1.7M
Uncontrolled hypertension - the role of medication adherence and clinical inertiaK23HL098359 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRONISH, IAN MATTHEW · 2010 to 2014
$688k
CELLULAR MECHANISMS OF ELECTRICAL ALTERNANSF32HL008817 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI RUBENSTEIN, DONALD S · 1993 to 1993
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TRANSLATIONAL BEHAVIORAL SCIENCE RESEARCH CONSORTIA-N01HC25197N01HC025197 · HC · MOUNT SINAI SCHOOL OF MEDICINE · 2002 to 2005
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NCATS NIH HHS UL1 TR000040NHLBI NIH HHS HC25197NHLBI NIH HHS HL08817NHLBI NIH HHS K23 HL098359NHLBI NIH HHS K23-HL098359NHLBI NIH HHS N01 HC025197NHLBI NIH HHS P01 HL088117NHLBI NIH HHS R01 HL115941PHS HHS 10SDG2600321
6 · The paper itself

Abstract

backgroundDepression is associated with poor adherence to medications and worse prognosis in patients with acute coronary syndrome (ACS). PURPOSE: To determine whether cognitive, behavioral, and/or psychosocial vulnerabilities for depression explain the association between depression and medication adherence among ACS patients.

methodsOne hundred sixty-nine ACS patients who agreed to have their aspirin adherence measured using an electronic pill bottle for 3 months were enrolled within 1 week of hospitalization. Linear regression was used to determine whether depression vulnerabilities predicted aspirin adherence after adjustment for depressive symptoms, demographics, and comorbidity.

resultsOf the depression vulnerabilities, only role transitions (beta = -3.32; P = 0.02) and interpersonal conflict (beta -3.78; P = 0.03) predicted poor adherence. Depression vulnerabilities did not mediate the association between depressive symptoms and medication adherence.

conclusionsKey elements of the psychosocial context preceding the ACS including major role transitions and conflict with close contacts place ACS patients at increased risk for poor medication adherence independent of depressive symptoms.

Indexed as

Interpersonal RelationsAcute Coronary SyndromeAdaptation, PsychologicalAgedAspirinDepressionFemaleHumansMaleMedication AdherenceMiddle AgedPlatelet Aggregation InhibitorsSeverity of Illness IndexAspirinPlatelet Aggregation Inhibitors

Identifiers

PMID24163188
PMCPMC3967002

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.