Evidence map›Paper›PMID 24162736›Full record

ArticleNature genetics2013

Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars.

Mingzhou Li, Shilin Tian, Long Jin, Guangyu Zhou, Ying Li, Yuan Zhang, Tao Wang, Carol K L Yeung, Lei Chen, Jideng Ma and 41 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 349 papers.

0numbers the graph read from it
0cells of the map it votes in
349citing papers in PubMed
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

349 citing papers in PubMed, 577 citations in OpenAlex.

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289 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

51 authors at 12 institutions in 3 countries.

Mingzhou Li1] Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an, China. [2] Biodynamic Optical Imaging Center (BIOPIC), Peking-Tsinghua Center for Life Sciences and School of Life Sciences, Peking University, Beijing, China. [3].
Shilin Tian
Long Jin
Guangyu Zhou
Ying Li
Yuan Zhang
Tao Wang
Carol K L Yeung
Lei Chen
Jideng Ma
Jinbo Zhang
Anan Jiang
Ji Li
Chaowei Zhou
Jie Zhang
Yingkai Liu
Xiaoqing Sun
Hongwei Zhao
Zexiong Niu
Pinger Lou
Lingjin Xian
Xiaoyong Shen
Shaoqing Liu
Shunhua Zhang
Mingwang Zhang
Li Zhu
Surong Shuai
Lin Bai
Guoqing Tang
Haifeng Liu
Yanzhi Jiang
Miaomiao Mai
Jian Xiao
Xun Wang
Qi Zhou
Zhiquan Wang
Paul Stothard
Ming Xue
Xiaolian Gao
Zonggang Luo
Yiren Gu
Hongmei Zhu
Xiaoxiang Hu
Yaofeng Zhao
Graham S Plastow
Jinyong Wang
Zhi Jiang
Kui Li
Ning Li
Xuewei Li
Ruiqiang Li
Sichuan Agricultural University · CNNovogene Bioinformatics Institute · CNChina Agricultural University · CNUniversity of Alberta · CAChongqing Academy of Animal Science · CNCenter for Life Sciences · CNChinese Academy of Agricultural Sciences · CNNational Animal Husbandry Service · CNSichuan Animal Science Academy · CNSouthwest University · CNUniversity of Houston · USYa'an Polytechnic College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the sequencing at 131× coverage, de novo assembly and analyses of the genome of a female Tibetan wild boar. We also resequenced the whole genomes of 30 Tibetan wild boars from six major distributed locations and 18 geographically related pigs in China. We characterized genetic diversity, population structure and patterns of evolution. We searched for genomic regions under selection, which includes genes that are involved in hypoxia, olfaction, energy metabolism and drug response. Comparing the genome of Tibetan wild boar with those of neighboring Chinese domestic pigs further showed the impact of thousands of years of artificial selection and different signatures of selection in wild boar and domestic pig. We also report genetic adaptations in Tibetan wild boar that are associated with high altitudes and characterize the genetic basis of increased salivation in domestic pig.

Indexed as

Selection, GeneticAdaptation, BiologicalAltitudeAnimalsEvolution, MolecularFemaleGenetic VariationGenomeMultigene FamilyPhylogenySalivationSequence Analysis, DNASus scrofaTibet

Identifiers

PMID24162736
OpenAlexW2075183916

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.