ArticleApplied and environmental microbiology2014
Glycine betaine as a direct substrate for methanogens (Methanococcoides spp.).
Article in Applied and environmental microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 75 citations in OpenAlex.
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- Rethinking the Esterquats: Synthesis, Stability, Ecotoxicity and Applications of Esterquats Incorporating Analogs of Betaine or Choline as the Cation in Their Structure.International journal of molecular sciences · 2024Review
- Methylotrophy in the Mire: direct and indirect routes for methane production in thawing permafrost.mSystems · 2024Article
- Unfolding and De-confounding: Biologically meaningful causal inference from longitudinal multi-omic networks using METALICA.bioRxiv : the preprint server for biology · 2023Article
- The Effect of Supplementation with Betaine and Zinc on In Vitro Large Intestinal Fermentation in Iberian Pigs under Heat Stress.Animals : an open access journal from MDPI · 2023Article
- Perspective on the use of methanogens in lithium recovery from brines.Frontiers in microbiology · 2023Article
- Methanogen activity and microbial diversity in Gulf of Cádiz mud volcano sediments.Frontiers in microbiology · 2023Article
- Ecology of Methanonatronarchaeia.Environmental microbiology · 2022Article
- Differences in the methanogen community between the nearshore and offshore sediments of the South Yellow Sea.Journal of microbiology (Seoul, Korea) · 2022Article
- Diverse methylotrophic methanogenic archaea cause high methane emissions from seagrass meadows.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Metaproteomics reveals methyltransferases implicated in dichloromethane and glycine betaine fermentation by 'Frontiers in microbiology · 2022Article
- Bacteria and Archaea Synergistically Convert Glycine Betaine to Biogenic Methane in the Formosa Cold Seep of the South China Sea.mSystems · 2021Article
- Anaerobic microbial methanol conversion in marine sediments.Environmental microbiology · 2021Review
- Archaeal Communities: The Microbial Phylogenomic Frontier.Frontiers in genetics · 2021Review
- Role ofApplied and environmental microbiology · 2020Article
- Several ways one goal-methanogenesis from unconventional substrates.Applied microbiology and biotechnology · 2020Review
- Biochemical and phylogenetic characterization of a monomeric isocitrate dehydrogenase from a marine methanogenic archaeon Methanococcoides methylutens.Extremophiles : life under extreme conditions · 2020Article
- A new family of uncultivated bacteria involved in methanogenesis from the ubiquitous osmolyte glycine betaine in coastal saltmarsh sediments.Microbiome · 2019Article
- Genome Sequences of Two Choline-Utilizing Methanogenic Archaea,Microbiology resource announcements · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nine marine methanogenic Methanococcoides strains, including the type strains of Methanococcoides methylutens, M. burtonii, and M. alaskense, were tested for the utilization of N-methylated glycines. Three strains (NM1, PM2, and MKM1) used glycine betaine (N,N,N-trimethylglycine) as a substrate for methanogenesis, partially demethylating it to N,N-dimethylglycine, whereas none of the strains used N,N-dimethylglycine or sarcosine (N-methylglycine). Growth rates and growth yields per mole of substrate with glycine betaine (3.96 g [dry weight] per mol) were similar to those with trimethylamine (4.11 g [dry weight] per mol). However, as glycine betaine is only partially demethylated, the yield per methyl group was significantly higher than with trimethylamine. If glycine betaine and trimethylamine are provided together, trimethylamine is demethylated to dimethyl- and methylamine with limited glycine betaine utilization. After trimethylamine is depleted, dimethylamine and glycine betaine are consumed rapidly, before methylamine. Glycine betaine extends the range of substrates that can be directly utilized by some methanogens, allowing them to gain energy from the substrate without the need for syntrophic partners.
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