Evidence map›Paper›PMID 24161197›Full record

ArticleACS nano2013

Slowing DNA translocation through a nanopore using a functionalized electrode.

Padmini Krishnakumar, Brett Gyarfas, Weisi Song, Suman Sen, Peiming Zhang, Predrag Krstić, Stuart Lindsay

Abstract read
In one paragraph

Article in ACS nano, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Nanopore sensing: A physical-chemical approach.Biochimica et biophysica acta. Biomembranes · 2021
    Review
  4. Article
  5. Article
  6. Graphene nanodevices for DNA sequencing.Nature nanotechnology · 2016
    Review
  7. Article
  8. Article
  9. Article
  10. Slowing DNA Transport Using Graphene-DNA Interactions.Advanced functional materials · 2015
    Article
  11. Article
  12. The evolution of nanopore sequencing.Frontiers in genetics · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Padmini KrishnakumarDepartment of Physics, ‡Biodesign Institute, and §Department of Chemistry and Biochemistry, Arizona State University , Tempe, Arizona 85287, United States.
Brett Gyarfas
Weisi Song
Suman Sen
Peiming Zhang
Predrag Krstić
Stuart Lindsay

Funding

Instrument to Optimize DNA Sequencing by Recognition TunnelingR01HG006323 · NHGRI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI LINDSAY, STUART · 2011 to 2015
$5.0M
NHGRI NIH HHS HG 006323NHGRI NIH HHS R01 HG006323
6 · The paper itself

Abstract

Nanopores were fabricated with an integrated microscale Pd electrode coated with either a hydrogen-bonding or hydrophobic monolayer. Bare pores, or those coated with octanethiol, translocated single-stranded DNA with times of a few microseconds per base. Pores functionalized with 4(5)-(2-mercaptoethyl)-1H-imidazole-2-carboxamide slowed average translocation times, calculated as the duration of the event divided by the number of bases translocated, to about 100 μs per base at biases in the range of 50 to 80 mV.

Indexed as

ElectrodesNanoporesBiological TransportDNADNA, Single-StrandedEquipment DesignHydrogen BondingMaterials TestingMembranes, ArtificialMicroscopy, Atomic ForceNanotechnologyNormal DistributionPalladiumSulfhydryl CompoundsSurface PropertiesTime FactorsDNADNA, Single-StrandedMembranes, ArtificialPalladiumSulfhydryl Compounds

Identifiers

PMID24161197
PMCPMC3875158

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.