ArticleOsong public health and research perspectives2013
Evaluation of the Effectiveness of Pandemic Influenza A(H1N1) 2009 Vaccine Based on an Outbreak Investigation During the 2010-2011 Season in Korean Military Camps.
Article in Osong public health and research perspectives, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Assessment of intensive vaccination and antiviral treatment in 2009 influenza pandemic in Korea.Osong public health and research perspectives · 2015Article
- Was the mass vaccination effective during the influenza pandemic 2009-2010 in Korea?Osong public health and research perspectives · 2013Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIn December 2010, there was an outbreak of acute febrile respiratory disease in many Korean military camps that were not geographically related. A laboratory analysis confirmed a number of these cases to be infected by the pandemic influenza A(H1N1) 2009 (H1N1pdm09) virus. Because mass vaccination against H1N1pdm09 was implemented at the infected military camps eleven months ago, the outbreak areas in which both vaccinated and nonvaccinated individuals were well mixed, gave us an opportunity to evaluate the effectiveness of H1N1pdm09 vaccine through a retrospective cohort study design.
methodsA self-administered questionnaire was distributed to the three military camps in which the outbreak occurred for case detection, determination of vaccination status, and characterization of other risk factors. The overall response rate was 86.8% (395/455). Case was defined as fever (≥38 °C) with cough or sore throat, influenza-like illness (ILI), and vaccination status verified by vaccination registry. Crude vaccine effectiveness (VE) was calculated as "1 - attack rate in vaccinated individuals/attack rate in nonvaccinated individuals", and adjusted VE was calculated as "1 - odds ratio" using logistic regression adjusted for potential confounding factor. A number of ILI definitions were used to test the robustness of the result.
resultsThe attack rate of ILI was 12.8% in register-verified vaccinated individuals and 24.0% in nonvaccinated individuals. The crude VE was thus calculated to be 46.8% [95% confidence interval (CI): 14.5-66.9]. The adjusted VE rate was 46.8% (95% CI: -9.4 to 74.1). Various combinations of ILI symptoms also showed similar VE rates.
conclusionWe evaluated the effectiveness of H1N1pdm09 vaccine in the 2010-2011 season in an outbreak setting. Although the result was not sensitive to any analytical method used and ILI case definition, the magnitude of effectiveness was lower than estimated in the 2009-2010 season.
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