Evidence map›Paper›PMID 24159374›Full record

ArticleJournal of materials chemistry. B2013

Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells

Hang Xing, Li Tang, Xujuan Yang, Kevin Hwang, Wendan Wang, Qian Yin, Ngo Yin Wong, Lawrence W Dobrucki, Norio Yasui, John A Katzenellenbogen and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of materials chemistry. B, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 193 citations in OpenAlex.

  1. Aptamers used for biosensors and targeted therapy.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
    Pooled it
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  11. Molecular Programming Design of Glyconucleic Acid Aptamer with High Stability.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Hang XingDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA. Tel: +1-217-333-2619 ; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA. Tel: +1-217-244-5023.
Li Tang
Xujuan Yang
Kevin Hwang
Wendan Wang
Qian Yin
Ngo Yin Wong
Lawrence W Dobrucki
Norio Yasui
John A Katzenellenbogen
William G Helferich
Jianjun Cheng
Yi Lu
University of Illinois Urbana-Champaign · US

Funding

Pharmacokinetics, Bioavailability, and Metabolism/Daniel R. DoergeP50AT006268 · NCCIH · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HELFERICH, WILLIAM G · 2010 to 2015
$7.6M
INSTITUTIONAL NRSA IN MOLECULAR BIOPHYSICST32GM008276 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI GROSMAN, CLAUDIO F · 1988 to 2013
$4.8M
Developing Clinically Applicable, Cancer-Targeting Polymeric NanoconjugatesDP2OD007246 · OD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHENG, JIANJUN · 2010 to 2010
$2.4M
Training the Next Generation of Researchers in Cancer Nanotechnology at the NCI MR25CA154015 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BASHIR, RASHID, NARDULLI, ANN · 2010 to 2014
$1.5M
Camptothecin-Containing Nanoparticles: Control Over Particle Size, BiodistributioR21CA152627 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHENG, JIANJUN · 2011 to 2012
$334k
NCCIH NIH HHS P50 AT006268NCI NIH HHS R21 CA152627NCI NIH HHS R25 CA154015NIGMS NIH HHS T32 GM008276NIH HHS DP2 OD007246
6 · The paper itself

Abstract

Selective targeting of cancer cells is a critical step in cancer diagnosis and therapy. To address this need, DNA aptamers have attracted significant attention as possible targeting ligands. However, while their use in targeting cancer cells

Indexed as

breast cancercancer targetingDNA aptamerliposomenucleolintargeted drug delivery

Identifiers

PMID24159374
PMCPMC3800741
OpenAlexW2100572625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.