Evidence map›Paper›PMID 24159061›Full record

ArticleStroke2013

Dietary patterns are associated with incident stroke and contribute to excess risk of stroke in black Americans.

Suzanne E Judd, Orlando M Gutiérrez, P K Newby, George Howard, Virginia J Howard, Julie L Locher, Brett M Kissela, James M Shikany

Abstract read
In one paragraph

Article in Stroke, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Suzanne E JuddFrom the Department of Biostatistics (S.E.J., G.H.), School of Public Health (S.E.J., O.M.G., G.H., V.J.H.), Division of Nephrology, Department of Medicine (O.M.G.), Department of Epidemiology (O.M.G., V.J.H.), Division of Gerontology, Geriatrics, and Palliative Care, Department of Medicine (J.L.L.), Division of Preventive Medicine, Department of Medicine, School of Medicine (J.M.S.), University of Alabama at Birmingham; Program in Gastronomy, Culinary Arts, and Wine Studies, Boston University, MA (P.K.N.); and Department of Neurology, School of Medicine, University of Cincinnati, OH (B.M.K.).
Orlando M Gutiérrez
P K Newby
George Howard
Virginia J Howard
Julie L Locher
Brett M Kissela
James M Shikany

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., TSEVAT, JOEL · 2012 to 2014
$9.9M
Translational Nutrition and Aging Research Academic Career Leadership AwardK07AG043588 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LOCHER, JULIE L. · 2012 to 2016
$583k
NCATS NIH HHS UL1 TR000077NCATS NIH HHS UL1 TR001425NIA NIH HHS K07 AG043588NIDDK NIH HHS P30 DK079626NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

background and purposeBlack Americans and residents of the Southeastern United States are at increased risk of stroke. Diet is one of many potential factors proposed that might explain these racial and regional disparities.

methodsBetween 2003 and 2007, the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort study enrolled 30 239 black and white Americans aged≥45 years. Dietary patterns were derived using factor analysis and foods from food frequency data. Incident strokes were adjudicated using medical records by a team of physicians. Cox-proportional hazards models were used to examine risk of stroke.

resultsDuring 5.7 years, 490 incident strokes were observed. In a multivariable-adjusted analysis, greater adherence to the plant-based pattern was associated with lower stroke risk (hazard ratio, 0.71; 95% confidence interval, 0.56-0.91; Ptrend=0.005). This association was attenuated after addition of income, education, total energy intake, smoking, and sedentary behavior. Participants with a higher adherence to the Southern pattern experienced a 39% increased risk of stroke (hazard ratio, 1.39; 95% confidence interval, 1.05, 1.84), with a significant (P=0.009) trend across quartiles. Including Southern pattern in the model mediated the black-white risk of stroke by 63%.

conclusionsThese data suggest that adherence to a Southern style diet may increase the risk of stroke, whereas adherence to a more plant-based diet may reduce stroke risk. Given the consistency of finding a dietary effect on stroke risk across studies, discussing nutrition patterns during risk screening may be an important step in reducing stroke.

Indexed as

DietAdultAgedAged, 80 and overBlack or African AmericanFemaleHumansIncidenceMaleMiddle AgedRisk FactorsStrokeWhite Peoplecontinental population groupsdietary habitsepidemiologyethnicitystroke

Identifiers

PMID24159061
PMCPMC3898713

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.