ArticleEuropean archives of psychiatry and clinical neuroscience2014
The effect of serotonin 1A receptor polymorphism on the cognitive function of premenstrual dysphoric disorder.
Article in European archives of psychiatry and clinical neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Premenstrual syndrome and alcohol consumption: a systematic review and meta-analysis.BMJ open · 2018Pooled it
- Impairment of Executive Functions in Premenstrual Syndrome: State or Trait?Biological psychiatry global open science · 2026Article
- Molecular Mechanisms of Menstrual Cycle-Related Suicide Risk: A Selective Review of Promising Candidate Systems.Biological psychiatry · 2026Review
- Pre and Post Menstruation Cognitive Functioning in Women with remenstrual Dysphoric Disorder, Premenstrual Syndrome and Controls: A Quasi Experimental Study.BMC women's health · 2025Article
- Association Study of Serotonin 1A Receptor Gene, Personality, and Anxiety in Women with Alcohol Use Disorder.International journal of molecular sciences · 2024Article
- Attention, response inhibition, impulsivity, and decision-making within luteal phase in women with premenstrual dysphoric disorder.Archives of women's mental health · 2023Article
- The potential role of the orexin system in premenstrual syndrome.Frontiers in endocrinology · 2023Review
- Early and Late Luteal Executive Function, Cognitive and Somatic Symptoms, and Emotional Regulation of Women with Premenstrual Dysphoric Disorder.Journal of personalized medicine · 2022Article
- Insomnia, Inattention and Fatigue Symptoms of Women with Premenstrual Dysphoric Disorder.International journal of environmental research and public health · 2021Article
- Cognition, The Menstrual Cycle, and Premenstrual Disorders: A Review.Brain sciences · 2020Review
- Association between Generalized Anxiety Disorder and Premenstrual Dysphoric Disorder in a Diagnostic Interviewing Study.International journal of environmental research and public health · 2020Article
- Early- and Late-Luteal-Phase Estrogen and Progesterone Levels of Women with Premenstrual Dysphoric Disorder.International journal of environmental research and public health · 2019Article
- Genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-HT1A receptor gene as a paradigmJournal of psychiatry & neuroscience : JPN · 2019Review
- Reproductive Affective Disorders: a Review of the Genetic Evidence for Premenstrual Dysphoric Disorder and Postpartum Depression.Current psychiatry reports · 2017Review
- Serotonin-1A receptor C-1019G polymorphism affects brain functional networks.Scientific reports · 2017Article
- Go and NoGo: modulation of electrophysiological correlates by female sex steroid hormones.Psychopharmacology · 2016Article
- The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription.Translational psychiatry · 2016Article
- Sex hormones affect neurotransmitters and shape the adult female brain during hormonal transition periods.Frontiers in neuroscience · 2015Review
- New aspects of cognition domains and psychopathological measures in psychiatry.European archives of psychiatry and clinical neuroscience · 2014Article
- Were there evolutionary advantages to premenstrual syndrome?Evolutionary applications · 2014Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Estrogen and serotonin play vital roles in the mechanism of premenstrual dysphoric disorder (PMDD). Cognitive deficit in the premenstrual phase contributes to impaired life function among women with PMDD. The aim of this study was to evaluate the difficulties in cognitive control and working memory (WM) in PMDD and to explore the effects of gonadotropic hormone and polymorphism of serotonin 1A receptor (HTR1A; rs6295) on cognitive deficit in PMDD. Women with PMDD completed diagnostic interviewing, questionnaire assessment, the Go/Nogo task, 2-back and 3-back tasks, and gonadotropic hormone analysis in the premenstrual and follicular phases. Further, they were followed up for two menstrual cycles to confirm two consecutive symptomatic cycles. A total of 59 subjects with PMDD and 74 controls completed all evaluation, fulfilled the criteria, and entered into the final analysis. The results demonstrated cognitive control and WM decline in the premenstrual among women with PMDD. The G/G genotype of HTR1A (rs6295) was found to be associated with impaired WM in the premenstrual phase and premenstrual decline of cognitive function. It also contributed to the vulnerability of cognitive function to the menstrual cycle effect and PMDD effect. As the G/G genotype of HTR1A (rs6295) involves in reducing serotonin neurotransmission, our results provide insight into the serotonin mechanism of cognitive function among women with PMDD.
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