ArticleObesity surgery2014
Gastric histopathology in laparoscopic sleeve gastrectomy: pre- and post-operative comparison.
Article in Obesity surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Is Routine Preoperative Esophagogastroduodenoscopy Prior to Bariatric Surgery Mandatory? Systematic Review and Meta-analysis of 10,685 Patients.Obesity surgery · 2020Pooled it
- Article
- Impact of Helicobacter pylori Status on Postoperative Morbidities After Laparoscopic Sleeve Gastrectomy in an Endemic Region (a Retrospective Multicentric Study).Obesity surgery · 2024Article
- The Effect of Helicobacter pylori Eradication on Gastric Wall Thickness in Patients Undergoing Laparoscopic Sleeve Gastrectomy.Obesity surgery · 2021Article
- The Relationship Between Histopathologic Findings and Weight Loss in Laparoscopic Sleeve Gastrectomy.Obesity surgery · 2020Article
- Quantitative and Topographic Analysis by Immunohistochemical Expression of Ghrelin Gastric Cells in Patients with Morbid Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Is routine preoperative esophagogastroduodenscopy prior to bariatric surgery mandatory? protocol for a systematic review and meta-analysis.International journal of surgery protocols · 2020Article
- Helicobacter Pylori Infection Prevalence and Histopathologic Findings in Laparoscopic Sleeve Gastrectomy.Obesity surgery · 2019Article
- The Relationship Between Histopathologic Findings and Body Mass Index in Sleeve Gastrectomy Materials.Obesity surgery · 2019Article
- Histopathological findings in laparoscopic sleeve gastrectomy specimens.Qatar medical journal · 2019Article
- Histopathological Findings in Morbid Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy: Does H. pylori Infection Effective on Pathological Changes?Obesity surgery · 2018Article
- Gastritis might be considered as a technical factor affecting laparoscopic sleeve gastrectomy.Journal of surgical case reports · 2018Article
- Histopathological Findings in Laparoscopic Sleeve Gastrectomy Specimens from Patients with Obesity in Saudi Arabia.Gastroenterology research and practice · 2018Article
- Gastritis in patients undergoing sleeve gastrectomy: Prevalence, ethnic distribution, and impact on glycemic.Medicine · 2017Observational
- Chronic Gastritis in Morbidly Obese Patients with Sleeve Gastrectomy.Electronic physician · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSleeve gastrectomy (SG) produces excellent results in weight reduction and resolution of comorbidities. The histology of the gastric mucosa can be affected by the surgical procedure, with alterations of inflammatory patterns. The objective of this study is to evaluate alterations of the inflammatory patterns of the gastric mucosa in SG and the results in weight loss and resolution of comorbidities.
methodsMorbidly obese patients were selected to undergo SG. Endoscopies were performed pre-operatively and post-operatively after 6 months, with an incisura and 3 cm before the pylorus biopsies. Data on weight, height, and associated diseases were collected. The data were compared, and the biopsies evaluate the inflammatory patterns.
resultsThere was a reduction of body weight with a pre-operative weight of 132.5 ± 15.7 kg and a post-operative weight of 95.8 ±10.6 kg with a p < 0.001. Also, the body mass index (BMI) was reduced significantly with a mean pre-operative of 42.6 ± 10.6 kg/m(2) and a post-operative of 30.9 ± 3.2 kg/m(2) with a p < 0.001. The comorbidities were all resolved or improved. The pattern of gastric histology showed chronic gastritis with inflammatory activity associated with Helicobacter pylori in 33.3 % of the patients, along with foveolar hyperplasia at 58.3 %. The chronic gastritis with discrete inflammatory activity was reduced by 16.7 %, and the foveolar hyperplasia was reduced by 33.3 %.
conclusionThe inflammatory alterations in the pre-operative period were mainly foveolar hyperplasia and chronic gastritis associated with H. pylori, and they were reduced in the post-operative period. A significant reduction of weight and BMI occurred, and a resolution of comorbidities was observed.
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