Evidence map›Paper›PMID 24158679›Full record

SynthesisJournal of autism and developmental disorders2014

Measuring anxiety as a treatment endpoint in youth with autism spectrum disorder.

Luc Lecavalier, Jeffrey J Wood, Alycia K Halladay, Nancy E Jones, Michael G Aman, Edwin H Cook, Benjamin L Handen, Bryan H King, Deborah A Pearson, Victoria Hallett and 6 more

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of autism and developmental disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05031364 (Effectiveness of Evidence-Based Mental Health Practices for Youth With Autism Supported by Online Consultation to Practitioners in Community and Navy Clinics), which is not on this map. Cited by 78 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05031364 narecruitingnot on this mapstarted 2021, after this paper: background citation

Effectiveness of Evidence-Based Mental Health Practices for Youth With Autism Supported by Online Consultation to Practitioners in Community and Navy Clinics

TypeinterventionalSponsorUniversity of California, Los AngelesRan2021 to 2026Enrolled100ConditionsAutismArmsBehavioral Interventions for Anxiety in Children with Autism (BIACA), Treatment-as-Usual Supplemented by Internet-Based Self-Instruction (MEYA)
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. How well can commonly used anxiety scales detect treatment outcomes in the context of autism?Autism : the international journal of research and practice · 2025
    Trial
  6. Trial
  7. Trial
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  9. Trial
  10. Trial
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Sensory Processing and Anxiety: Within and Beyond the Autism Spectrum.Current topics in behavioral neurosciences · 2025
    Review
  18. Article
  19. Review
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Luc LecavalierDepartment of Psychology and Nisonger Center, Ohio State University, Columbus, OH, USA.
Jeffrey J Wood
Alycia K Halladay
Nancy E Jones
Michael G Aman
Edwin H Cook
Benjamin L Handen
Bryan H King
Deborah A Pearson
Victoria Hallett
Katherine Anne Sullivan
Sabrina Grondhuis
Somer L Bishop
Joseph P Horrigan
Geraldine Dawson
Lawrence Scahill

Funding

Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
Toward Outcome Measurement of Anxiety in Youth with Autism Spectrum DisordersR01MH099021 · NIMH · YALE UNIVERSITY · PI SCAHILL, LAWRENCE D. · 2012 to 2015
$2.7M
Treatment of Autism Symptoms in Children (TASC): Initial RCT with Active ControlR01MH094391 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WOOD, JEFFREY JAMES · 2012 to 2016
$1.9M
NCATS NIH HHS UL1 TR000371NIMH NIH HHS R01 MH094391NIMH NIH HHS R01 MH099021
6 · The paper itself

Abstract

Despite the high rate of anxiety in individuals with autism spectrum disorder (ASD), measuring anxiety in ASD is fraught with uncertainty. This is due, in part, to incomplete consensus on the manifestations of anxiety in this population. Autism Speaks assembled a panel of experts to conduct a systematic review of available measures for anxiety in youth with ASD. To complete the review, the panel held monthly conference calls and two face-to-face meetings over a fourteen-month period. Thirty eight published studies were reviewed and ten assessment measures were examined: four were deemed appropriate for use in clinical trials, although with conditions; three were judged to be potentially appropriate, while three were considered not useful for clinical trials assessing anxiety. Despite recent advances, additional relevant, reliable and valid outcome measures are needed to evaluate treatments for anxiety in ASD.

Indexed as

AdolescentAnxietyChildChild Development Disorders, PervasiveHumansMaleTreatment Outcome

Identifiers

PMID24158679
PMCPMC3981870

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.