Evidence map›Paper›PMID 24158582›Full record

Trial reportJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2013

Three-dimensional analysis of initial biofilm formation on polytetrafluoroethylene in the oral cavity.

C Fuchslocher Hellemann, S Grade, W Heuer, M P Dittmer, M Stiesch, R Schwestka-Polly, A P Demling

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Antibacterial properties and abrasion-stability: Development of a novel silver-compound material for orthodontic bracket application.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2024
    Article
  2. Review
  3. Article
  4. Comparison of intraoral biofilm reduction on silver-coated and silver ion-implanted stainless steel bracket material : Biofilm reduction on silver ion-implanted bracket material.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2019
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C Fuchslocher HellemannDepartment of Orthodontics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
S Grade
W Heuer
M P Dittmer
M Stiesch
R Schwestka-Polly
A P Demling

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThere is published evidence that polytetrafluoroethylene (PTFE) exhibits beneficial surface characteristics by means of long-term biofilm accumulation. The purpose of this study was to investigate and compare early biofilm formation on polytetrafluoroethylene, ceramic-reinforced polytetrafluoroethylene and as the control group, stainless steel. MATERIALS AND

methodsThis study comprised 10 healthy volunteers (5 females and 5 males) with a mean age of 27.3 ± 3.7 years. Three different slabs (two PTFE coatings: one pure and one ceramic-reinforced polytetrafluoroethylene, and stainless steel) were placed in random order on a splint in the mandibular molar region. Intraoral splints were inserted for 48 h. After 48 h, we removed the slabs from the splints and stained the biofilm with a two-color fluorescence assay for bacterial viability (LIVE/DEAD BacLight-Bacterial Viability Kit 7012, Invitrogen, Mount Waverley, Australia). The amount of biofilm accumulation was assessed using confocal laser scanning microscopy (CLSM).

resultsThe biofilm surface coverage was 55.8 ± 39.8% on pure PTFE-coated probes, 55.9 ± 35.0% on ceramic-reinforced PTFE-coated probes, and 33.3 ± 37.8% on stainless steel. The differences among the three groups were not significant (p = 0.301). Biofilm depth was 5.6 ± 5.4 μm on pure PTFE-coated probes, 5.2 ± 3.8 μm on ceramic-reinforced PTFE-coated probes, and 2.4 ± 2.9 μm on stainless steel. The Friedman test revealed a significant difference in biofilm depth (p = 0.002). Pairwise comparison of biofilm accumulation yielded a significant difference between pure PTFE and ceramic-reinforced PTFE compared to stainless steel (p = 0.017; p = 0.005).

conclusionOur results indicate that the beneficial surface characteristics of PTFE coatings by reducing long-term biofilm are not a result of inhibiting initial bacterial adhesion.

Indexed as

PolytetrafluoroethyleneAdultBacteriaBacterial AdhesionBiofilmsCoated Materials, BiocompatibleDental MaterialsFemaleHumansImaging, Three-DimensionalMaleMaterials TestingMicroscopy, ConfocalMouthOrthodontic BracketsReference ValuesCoated Materials, BiocompatibleDental MaterialsPolytetrafluoroethylene

Identifiers

PMID24158582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.