ReviewCurrent hypertension reports2013
Blood pressure levels and stroke: J-curve phenomenon?
Review in Current hypertension reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Low Diastolic Blood Pressure is Not Related to Risk of First Episode of Stroke in a High-Risk Population: A Secondary Analysis of SPRINT.Journal of the American Heart Association · 2019Trial
- Trial
- Functional Status and Antihypertensive Therapy in Older Adults: A New Perspective on Old Data.American journal of hypertension · 2016Trial
- Achieved Blood Pressure and Outcomes in the Secondary Prevention of Small Subcortical Strokes Trial.Hypertension (Dallas, Tex. : 1979) · 2016Trial
- Non-linear association and benchmark dose of blood pressure on carotid artery intima-media thickening in a general population of southern China.Frontiers in cardiovascular medicine · 2024Article
- On the definition of dermatological disease. Part 2: approaches for defining dermatological diseases.Clinical and experimental dermatology · 2022Review
- A fluid-structure interaction model accounting arterial vessels as a key part of the blood-flow engine for the analysis of cardiovascular diseases.Frontiers in bioengineering and biotechnology · 2022Article
- Effect of SLGT2 Inhibitors on Patients with Atrial Fibrillation.Journal of atrial fibrillation · 2021Article
- Epidemiology of hypertensive heart disease in Poland: findings from the Global Burden of Disease Study 2016.Archives of medical science : AMS · 2021Article
- Lifetime predictors of stroke in subjects without a diagnosis of hypertension: the aerobics center longitudinal study.Neuropsychiatric disease and treatment · 2019Article
- Low Pulse Pressure After Acute Ischemic Stroke is Associated With Unfavorable Outcomes: The Taiwan Stroke Registry.Journal of the American Heart Association · 2017Article
- Relationship Between Blood Pressure Values, Depressive Symptoms, and Cardiovascular Outcomes in Patients With Cardiometabolic Disease.Journal of clinical hypertension (Greenwich, Conn.) · 2016Article
- Cardiovascular diseases in patients 65 years and younger with non-cardiogenic stroke.Archives of medical science : AMS · 2016Article
- Improvement of survival in Polish stroke patients is related to reduced stroke severity and better control of risk factors: the Krakow Stroke Database.Archives of medical science : AMS · 2016Article
- Effects of dialyzer reuse on dialysis adequacy, anemia control, erythropoieting-stimulating agents use and phosphate level.Archives of medical science : AMS · 2016Article
- Commentary on recent guidelines for treating hypertension.Archives of medical science : AMS · 2014Article
- Lipid, blood pressure and kidney update 2013.International urology and nephrology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The blood pressure J-curve discussion has been ongoing for more than 30 years, yet there are still questions in need of definitive answers. On one hand, existing antihypertensive therapy studies provide strong evidence for J-curve-shaped relationships between both diastolic and systolic blood pressure and primary outcomes in the general hypertensive patient population, as well as in high-risk populations, including subjects with coronary artery disease, diabetes mellitus, left ventricular hypertrophy, and the elderly. On the other hand, we have very limited data on the relationship between systolic and diastolic blood pressure and stroke prevention. Moreover, it seems that this outcome is more a case of "the lower the better." Further large, well-designed studies are necessary in order to clarify this issue, especially as existing available studies are observational, and randomized trials either did not have or lost statistical power and were thus inconclusive.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.