SynthesisCurrent hypertension reports2013
Blood pressure control and primary prevention of stroke: summary of the recent clinical trial data and meta-analyses.
Synthesis in Current hypertension reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Perceived social support and ambulatory blood pressure during daily life: a meta-analysis.Journal of behavioral medicine · 2022Pooled it
- Combining angiotensin receptor blockers with chlorthalidone or hydrochlorothiazide - which is the better alternative? A meta-analysis.Systematic reviews · 2020Pooled it
- Japanese steam sand bath heat therapy mediates comparable reductions in blood pressure with smaller discomfort and respiratory strains than hot water immersion and sauna.European journal of applied physiology · 2026Trial
- Perspectives of older people engaging in nurse-led cardiovascular prevention programmes: a qualitative study in primary care in the Netherlands.The British journal of general practice : the journal of the Royal College of General Practitioners · 2015Trial
- GWAS reveals common SLX4 variants associated with telomere length and hypertension in individuals of African ancestry.Genes & genomics · 2026Article
- Regulating the Impact of Hypertension on Stroke: Therapeutic Potential of a Peptide Mimetic of Tyrosine Phosphatase STEP.Journal of the American Heart Association · 2026Article
- Association between nutrition literacy and hypertension control: chain mediating association of diet-control intention and salt-restriction tools utilization.Frontiers in nutrition · 2026Article
- Intensified blood pressure control during hospital admission and on discharge: a systematic review and meta-analysis of retrospective cohort studies.Frontiers in cardiovascular medicine · 2026Review
- Relationship Between Subclinical Renal Damage and Maximum Rate of Blood Pressure Variation Assessed by Fourier Analysis of 24-h Blood Pressure Curve in Patients with Essential Hypertension.Life (Basel, Switzerland) · 2025Article
- Both hot- and thermoneutral-water immersion reduce 24-h blood pressure in people with hypertension: A randomized crossover study.Temperature (Austin, Tex.) · 2025Article
- Time in target range for systolic blood pressure and stroke in people with and without diabetes: the Kailuan prospective cohort study.Frontiers in endocrinology · 2025Article
- Ischemic Stroke in Women: Understanding Sex-Specific Risk Factors, Treatment Considerations, and Outcomes.Journal of cardiovascular development and disease · 2024Review
- Position statement on hypertension by Indian Society of Hypertension, 2023.Journal of human hypertension · 2024Article
- Promise of Lifestyle Medicine for Heart Disease, Diabetes Mellitus, and Cerebrovascular Diseases.Mayo Clinic proceedings. Innovations, quality & outcomes · 2024Article
- The Role of Circadian Rhythms in Stroke: A Narrative Review.Neurochemical research · 2024Review
- Epidemiology, Pathophysiology, and Current Treatment Strategies in Stroke.Cardiology and cardiovascular medicine · 2024Article
- Untreated hypertension and prognosis paradox in acute ischemic stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Acute and adaptive cardiovascular and metabolic effects of passive heat therapy or high-intensity interval training in patients with severe lower-limb osteoarthritis.Physiological reports · 2023Article
- Estimation of Life's Essential 8 Score with Incomplete Data of Individual Metrics.medRxiv : the preprint server for health sciences · 2023Article
- Estimation of life's essential 8 score with incomplete data of individual metrics.Frontiers in cardiovascular medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stroke is the second most common cause of death worldwide and of adult disability, but in the near future the global burden of cerebrovascular diseases will rise due to ageing and adverse lifestyle changes in populations worldwide. The risk of stroke increases at blood pressure levels above 115/75 mm Hg and high blood pressure (BP) is the most important modifiable risk factor for stroke, associated with 54 % episodes of stroke worldwide. There is strong evidence from clinical trials that antihypertensive therapy reduces substantially the risk of any type of stroke, as well as stroke-related death and disability. The risk attributed to BP is associated not only with absolute values but also with certain parameters describing BP diurnal pattern as well as short-term and long-term variability. Many studies reported that certain features of BP like nocturnal hypertension, morning surge or increased variability predict an increased stroke risk. However, there is no accepted effective modality for correction of these disturbances (chronotherapy, certain classes of antihypertensive drugs). In the elderly, who are mostly affected by stroke, the primary prevention guidelines recommend treatment with diuretics and calcium channel blockers to lower blood pressure to the standard level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.