ArticleThe Journal of biological chemistry2013
Translational regulation of Yersinia enterocolitica mRNA encoding a type III secretion substrate.
Article in The Journal of biological chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- RNase-mediated reprogramming of Yersinia virulence.PLoS pathogens · 2024Article
- Macrophage innate immune responses delineate between defective translocon assemblies produced byVirulence · 2023Article
- Article
- Article
- Campylobacteriosis, Salmonellosis, Yersiniosis, and Listeriosis as Zoonotic Foodborne Diseases: A Review.International journal of environmental research and public health · 2018Review
- Heterologous Complementation Studies With the YscX and YscY Protein Families Reveals a Specificity forFrontiers in cellular and infection microbiology · 2018Article
- Discovering RNA-Based Regulatory Systems forFrontiers in cellular and infection microbiology · 2018Review
- Enteropathogens: Tuning Their Gene Expression for Hassle-Free Survival.Frontiers in microbiology · 2018Review
- A systematic analysis of the RNA-targeting potential of secreted bacterial effector proteins.Scientific reports · 2017Article
- RNA-based mechanisms of virulence control in Enterobacteriaceae.RNA biology · 2017Review
- Post-transcriptional regulation of type III secretion in plant and animal pathogens.Current opinion in microbiology · 2017Review
- Yersinia Type III Secretion System Master Regulator LcrF.Journal of bacteriology · 2015Review
- Random mutagenesis identifies a C-terminal region of YopD important for Yersinia type III secretion function.PloS one · 2015Article
- Regulatory principles governing Salmonella and Yersinia virulence.Frontiers in microbiology · 2015Review
- RNA-binding proteins involved in post-transcriptional regulation in bacteria.Frontiers in microbiology · 2015Review
- LcrQ blocks the role of LcrF in regulating the Ysc-Yop type III secretion genes in Yersinia pseudotuberculosis.PloS one · 2014Article
- Piericidin A1 BlocksmSphereArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Yersinia enterocolitica type III secretion machines transport YopQ and other Yop effectors into host immune cells. YopD and its chaperone LcrH are essential components of the Yersinia type III pathway, enabling effector translocation into host cells. YopD, LcrH, and YscM1 also regulate yop expression post-transcriptionally in response to environmental signals; however, the molecular mechanisms for this regulation and Yop secretion are unknown. We show here that YopD associates with 30 S ribosomal particles in a manner requiring LcrH. When added to ribosomes, YopD, LcrH, and YscM1 block the translation of yopQ mRNA. We propose a model whereby LcrH-dependent association of YopD with 30 S ribosomal particles enables YscM1 to block yopQ translation unless type III machines are induced to secrete the effector.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.