SynthesisJournal of dental research2013
Dental implants installed in irradiated jaws: a systematic review.
Synthesis in Journal of dental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 7 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Survival rate and risk factors of implants in patients with head and neck neoplasms: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Clinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case series.BMC oral health · 2025Pooled it
- Survival of dental implants in irradiated head and neck cancer patients compared to non-irradiated patients: An umbrella review.PloS one · 2025Pooled it
- Current landmarks for gingival thickness evaluation in maxillary anterior teeth: a systematic review.Clinical oral investigations · 2023Pooled it
- Smoking and Dental Implants: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2021Pooled it
- Survival of dental implants and occurrence of osteoradionecrosis in irradiated head and neck cancer patients: a systematic review and meta-analysis.Clinical oral investigations · 2021Pooled it
- Pooled it
- Review
- HBOT as a Potential Adjunctive Therapy for Wound Healing in Dental Surgery-A Narrative Review.Journal of clinical medicine · 2026Review
- The Longitudinal Impact of Radiotherapy on Osseointegrated Hearing Aid Outcomes and Complications.The Laryngoscope · 2025Article
- Implant-Supported Oral Rehabilitation in Head and Neck Cancer Patients: A 20-Year Single-Center Study (2005-2024).Journal of clinical medicine · 2025Article
- Microbiological findings of dental implants among irradiated head and neck cancer patients.Bioinformation · 2025Article
- Therapeutic potential of carbon dots fromAnnals of translational medicine · 2024Article
- Prosthetic Rehabilitation Options in Post-Ablative Maxillomandibular Microvascular Reconstructions.Journal of maxillofacial and oral surgery · 2023Review
- The dose-dependent impact of γ-radiation reinforced with backscatter from titanium on primary human osteoblasts.Biomaterial investigations in dentistry · 2023Article
- Clinical long-term and patient-reported outcomes of dental implants in oral cancer patients.International journal of implant dentistry · 2021Article
- UV-Mediated Photofunctionalization of Dental Implant: A Seven-Year Results of a Prospective Study.Journal of clinical medicine · 2020Article
- Masticatory performance and oral health-related quality of life in edentulous maxillectomy patients: A cross-sectional study to compare implant-supported obturators and conventional obturators.Clinical oral implants research · 2020Article
- Systemic and local effects of radiotherapy: an experimental study on implants placed in rats.Clinical oral investigations · 2020Article
- How old is old for implant therapy in terms of early implant losses?Journal of clinical periodontology · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to assess the survival rate of titanium implants placed in irradiated jaws. MEDLINE, EMBASE, and CENTRAL were searched for studies assessing implants that had been placed in nongrafted sites of irradiated patients. Random effects meta-analyses assessed implant loss in irradiated versus nonirradiated patients and in irradiated patients treated with hyperbaric oxygen (HBO) therapy. Of 1,051 potentially eligible publications, 15 were included. A total of 10,150 implants were assessed in the included studies, and of these, 1,689 (14.3%) had been placed in irradiated jaws. The mean survival rate in the studies ranged from 46.3% to 98.0%. The pooled estimates indicated a significant increase in the risk of implant failure in irradiated patients (risk ratio: 2.74; 95% confidence interval: 1.86, 4.05; p < .00001) and in maxillary sites (risk ratio: 5.96; 95% confidence interval: 2.71, 13.12; p < .00001). Conversely, HBO therapy did not reduce the risk of implant failure (risk ratio: 1.28; 95% confidence interval: 0.19, 8.82; p = .80). Radiotherapy was linked to higher implant failure in the maxilla, and HBO therapy did not improve implant survival. Most included publications reported data on machined implants, and only 3 studies on HBO therapy were included. Overall, implant therapy appears to be a viable treatment option for reestablishing adequate occlusion and masticatory conditions in irradiated patients.
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