ArticleLaser therapy2013
830 nm light-emitting diode low level light therapy (LED-LLLT) enhances wound healing: a preliminary study.
Article in Laser therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- Photobiomodulation therapy with an 830-nm light-emitting diode for the prevention of thyroidectomy scars: a randomized, double-blind, sham device-controlled clinical trial.Lasers in medical science · 2022Trial
- Effect of low-level light therapy in patients with dry eye: a prospective, randomized, observer-masked trial.Scientific reports · 2022Trial
- The effect of LED on blood microcirculation during chronic wound healing in diabetic and non-diabetic patients-a prospective, double-blind randomized study.Lasers in medical science · 2017Trial
- Promotive effects of 830-nm Photobiomodulation on corneal epithelial wound healing and rho-gtpase expression in a rat alkali burn model.Lasers in medical science · 2026Article
- Photobiomodulation therapy enhances surfactant production in premature rat lungs: a non-invasive therapeutic strategy for neonatal respiratory distress syndromes.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Article
- Perovskites to Photonics: Engineering NIR LEDs for Photobiomodulation.Micromachines · 2025Article
- The Use of a Proprietary Near-Infrared Laser to Enhance Wound Healing: A Preliminary Preclinical and Clinical Study.Aesthetic surgery journal. Open forum · 2025Article
- Light-emitting diode phototherapy: pain relief and underlying mechanisms.Lasers in medical science · 2022Review
- Effect of Low-Level Laser Therapy on Bacterial Counts of Contaminated Traumatic Wounds in Dogs.Journal of lasers in medical sciences · 2021Article
- The Combination of Antimicrobial Photodynamic Therapy and Photobiomodulation Therapy for the Treatment of Palatal Ulcers: A Case Report.Journal of lasers in medical sciences · 2020Article
- Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light.The journal of pain · 2019Article
- Phototherapy with Light Emitting Diodes: Treating a Broad Range of Medical and Aesthetic Conditions in Dermatology.The Journal of clinical and aesthetic dermatology · 2018Review
- Effects of the led therapy on the global DNA methylation and the expression of Dnmt1 and Dnmt3a genes in a rat model of skin wound healing.Lasers in medical science · 2016Article
- Different effects of energy dependent irradiation of red and green lights on proliferation of human umbilical cord matrix-derived mesenchymal cells.Lasers in medical science · 2016Article
- Adjunctive 830 nm light-emitting diode therapy can improve the results following aesthetic procedures.Laser therapy · 2015Article
- Effect of light-emitting diode (ʎ 627 nm and 945 nm ʎ) treatment on first intention healing: immunohistochemical analysis.Lasers in medical science · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe application of light-emitting diodes in a number of clinical fields is expanding rapidly since the development in the late 1990s of the NASA LED. Wound healing is one field where low level light therapy with LEDs (LED-LLLT) has attracted attention for both accelerating wound healing and controlling sequelae. The present study evaluated LED-LLLT in 5 wounds of various etiologies. SUBJECTS AND
methodsThere were 5 patients with ages ranging from 7 to 54 years, comprising 2 males and 3 females. The study followed 5 wounds, namely 2 acute excoriation wounds; 1 acute/subacute dog bite with infection; 1 subacute post-filler ulcerated wound with necrotic ischemic tissue and secondary infection; and 1 subacute case of edema and infection of the lips with herpes simplex involvement after an illegal cosmetic tattoo operation. All patients were in varying degrees of pain. All wounds were treated with multiple sessions (daily, every other day or twice weekly) using an LED-LLLT system (830 nm, CW, irradiance of 100 mW/cm(2) and fluence of 60 J/cm(2)) till improvement was achieved.
resultsFull wound healing and control of infection and discomfort were achieved in all patients, with wound condition-mediated treatment periods ranging from 1 to 8 weeks. No recurrence of the herpes simplex case was seen in a 4-month follow-up.
conclusions830 nm LED-LLLT successfully brought about accelerated healing in wounds of different etiologies and at different stages, and successfully controlled secondary infection. LED-LLLT was easy and pain-free to apply, and was well-tolerated by all patients. The good results warrant the design of controlled studies with a larger patient population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.