ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2014
A review of the positive and negative effects of cardiovascular drugs on sexual function: a proposed table for use in clinical practice.
Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 76 citations in OpenAlex.
- Sexual function among controlled and uncontrolled hypertensive females receiving beta-blockers or ACEI/ARB and thiazides: a prospective randomized controlled study.Scientific reports · 2026Trial
- Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives.International journal of molecular sciences · 2026Review
- Common Determinants of Blood Pressure and Testosterone LevelReply.Arquivos brasileiros de cardiologia · 2024Article
- Prevalence of Cardiovascular Drugs and Oral Anticoagulant Use among Persons with and without Parkinson's Disease.Cardiology · 2024Article
- Heart Failure and Erectile Dysfunction: a Review of the Current Evidence and Clinical Implications.Current heart failure reports · 2023Review
- Genetically predicted hypertension, antihypertensive drugs, and risk of erectile dysfunction: a Mendelian randomization study.Frontiers in cardiovascular medicine · 2023Article
- Patient reporting of sexual adverse events on an online platform for medication experiences.British journal of clinical pharmacology · 2022Article
- Psychosexual Health and Sexual Medicine in Consultation-Liaison Psychiatry.Indian journal of psychiatry · 2022Article
- Interactions between erectile dysfunction, cardiovascular disease and cardiovascular drugs.Nature reviews. Cardiology · 2022Review
- Frequency of Iatrogenic Sexual Dysfunction Associated with Antihypertensive Compounds.Journal of clinical medicine · 2021Article
- An estimation of patients at potential risk for drug-induced sexual dysfunction using pharmacy dispensing data.Family practice · 2021Article
- Comparison of Effect of Nebivolol and Bisoprolol on Sexual Function of Hypertensive Female Patients.Cureus · 2021Article
- Sexual Dysfunction and the Impact of Beta-Blockers in Young Males With Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021Article
- Sexual Function in Men Living With a Fontan Circulation.Frontiers in pediatrics · 2021Article
- Erectile Dysfunction and Ischaemic Heart Disease.European cardiology · 2018Review
- Sexual dysfunction as a determinant of cardiovascular outcome in patients undergoing chronic hemodialysis.International journal of impotence research · 2018Article
- Attitudes and Performance of Cardiologists Toward Sexual Issues in Cardiovascular Patients.Sexual medicine · 2017Article
- The Different Therapeutic Choices with ARBs. Which One to Give? When? Why?American journal of cardiovascular drugs : drugs, devices, and other interventions · 2016Review
- Sexual counselling for patients with cardiovascular disease: protocol for a pilot study of the CHARMS sexual counselling intervention.BMJ open · 2016Article
- Does total hip replacement affect sexual quality of life?BMC musculoskeletal disorders · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several antihypertensive drugs, such as diuretics and β-blockers, can negatively affect sexual function, leading to diminished quality of life and often to noncompliance with the therapy. Other drug classes, however, such as angiotensin II receptor blockers (ARBs) are able to improve patients' sexual function. Sufficient knowledge about the effects of these widely used antihypertensive drugs will make it possible for cardiologists and general practitioners to spare and even improve patients' sexual health by switching to different classes of cardiac medication. Nevertheless, previous data (part I) indicate that most cardiologists lack knowledge about the effects cardiovascular agents can have on sexual function and will thus not be able to provide the necessary holistic patient care with regard to prescribing these drugs. To be able to improve healthcare on this point, we aimed to provide a practical overview, for use by cardiologists as well as other healthcare professionals, dealing with sexual dysfunction in their clinical practices. Therefore, a systematic review of the literature was performed. The eight most widely used classes of antihypertensive drugs have been categorised in a clear table, marking whether they have a positive, negative or no effect on sexual function.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.