Trial reportChinese journal of integrative medicine2014
Effects of acupuncture on Chinese medicine syndromes of vascular dementia.
Trial report in Chinese journal of integrative medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The effect of acupuncture on oxidative stress in animal models of vascular dementia: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- A network meta-analysis on the improvement of cognition in patients with vascular dementia by different acupuncture therapies.Frontiers in neuroscience · 2022Pooled it
- Pooled it
- Traditional Chinese herbal medicine for vascular dementia.The Cochrane database of systematic reviews · 2018Pooled it
- Korean medicine registry for cognitive disorder: A protocol for prospective observational multi-center study.PloS one · 2025Article
- Microbiota-gut-brain-axis: a new target of acupuncture therapy for post-stroke cognitive impairment.Frontiers in microbiology · 2025Review
- Acupuncture regulates the Th17/Treg balance and improves cognitive deficits in a rat model of vascular dementia.Heliyon · 2023Article
- The effects and mechanisms of acupuncture for post-stroke cognitive impairment: progress and prospects.Frontiers in neuroscience · 2023Review
- Quality of the Evidence Supporting the Role of Acupuncture Interventions for Vascular Dementia.Neuropsychiatric disease and treatment · 2023Review
- Lateralized brain activities in subcortical vascular mild cognitive impairment with differential Chinese medicine patterns: A resting-state functional magnetic resonance imaging study.Frontiers in neuroscience · 2022Article
- Acupuncture May Decrease the Incidence of Post-stroke Dementia: A Taiwan Nationwide Retrospective Cohort Study.Frontiers in neurology · 2021Article
- The effect of scalp electroacupuncture combined with Memantine in patients with vascular dementia: A retrospective study.Medicine · 2020Article
- Acupuncture Attenuates Inflammation in Microglia of Vascular Dementia Rats by Inhibiting miR-93-Mediated TLR4/MyD88/NF-Oxidative medicine and cellular longevity · 2020Article
- Acupuncture Improves White Matter Perfusion and Integrity in Rat Model of Vascular Dementia: An MRI-Based Imaging Study.Frontiers in aging neuroscience · 2020Article
- Acupuncture as a multifunctional neuroprotective therapy ameliorates cognitive impairment in a rat model of vascular dementia: A quantitative iTRAQ proteomics study.CNS neuroscience & therapeutics · 2018Article
- Acupuncture inhibits TXNIP-associated oxidative stress and inflammation to attenuate cognitive impairment in vascular dementia rats.CNS neuroscience & therapeutics · 2018Article
- Acupuncture Rescues Cognitive Impairment and Upregulates Dopamine-BioMed research international · 2018Article
- Article
- Acupuncture attenuates cognitive deficits and increases pyramidal neuron number in hippocampal CA1 area of vascular dementia rats.BMC complementary and alternative medicine · 2015Article
- Integrative neurobiological mechanisms of acupuncture in post-stroke cognitive impairment: from neurotransmission to brain network remodeling.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the effects of acupuncture on Chinese medicine syndromes of vascular dementia (VaD).
methodsSixty-three VaD patients were divided into three groups. Those willing to be randomized were randomly assigned to receive either acupuncture (random acupuncture group, 24 cases) or rehabilitation training (guided rehabilitation group, 24 cases) for 6 weeks. Those unwilling to be randomized also received acupuncture for 6 weeks (non-random acupuncture group, 19 cases). Patient syndromes and their severity were evaluated before treatment (baseline), at the end of treatment, and at 4-week follow-up after the completion of treatment using a CM scoring system (scale of differentiation of syndromes of vascular dementia, SDSVD). The SDSVD scores of the random and non-random acupuncture groups, and of all patients who received acupuncture (combined acupuncture group, 43 cases), were compared with those in the guided rehabilitation group.
resultsIn the random, non-random, and combined acupuncture groups, SDSVD scores were significantly reduced at the end of treatment and at follow-up than at baseline. In the guided rehabilitation group, SDSVD scores were similar to baseline scores at the end of treatment and at follow-up. However, there were no significant differences in SDSVD scores among the three groups or between the combined acupuncture group and the guided rehabilitation group at any time points. In the non-random and combined acupuncture groups, SDSVD scores were significantly reduced at the end of treatment than at baseline in patients with hyperactivity of Liver (Gan)-yang or phlegm obstruction of the orifices.
conclusionsAcupuncture reduced the severity of VaD. The improvement was the greatest in patients undergoing their treatment of choice. Treatments in this study were more effective for excess syndromes, such as Liver-yang hyperactivity or phlegm obstruction of the orifices than deficiency syndromes, such as Kidney (Shen)-essence deficiency.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.