ArticleThe journal of nutrition, health & aging2013
Association between illness progression measures and total cost in Alzheimer's disease.
Article in The journal of nutrition, health & aging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Cost of care for persons with dementia: using a discrete-time Markov chain approach with administrative and clinical data from the dementia service Centres in Austria.Health economics review · 2020Article
- Acute Healthcare Utilization of a Multidisciplinary Neurocognitive Dementia Patient Cohort.Journal of clinical neurology (Seoul, Korea) · 2020Article
- Multidimensional assessment of challenging behaviors in advanced stages of dementia in nursing homes-The insideDEM framework.Alzheimer's & dementia (Amsterdam, Netherlands) · 2017Article
- Trends, Predictors, and Outcomes of Healthcare Resources Used in Patients Hospitalized with Alzheimer's Disease with at Least One Procedure: The Nationwide Inpatient Sample.Journal of Alzheimer's disease : JAD · 2017Article
- Closer caregiver and care-recipient relationships predict lower informal costs of dementia care: The Cache County Dementia Progression Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2016Article
- Dementia severity and the longitudinal costs of informal care in the Cache County population.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2015Article
- Major Cost Drivers in Assessing the Economic Burden of Alzheimer's Disease: A Structured, Rapid Review.The journal of prevention of Alzheimer's diseaseReview
- Dependence Stage and Pharmacoeconomic Outcomes in Patients With Alzheimer Disease.Alzheimer disease and associated disordersArticle
- Disease Progression in Mild Dementia due to Alzheimer Disease in an 18-Month Observational Study (GERAS): The Impact on Costs and Caregiver Outcomes.Dementia and geriatric cognitive disorders extraArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the associations between dependence and clinical measures of cognition, function and behaviour and total care cost using data from a longitudinal study in Alzheimer's disease (AD).
designLongitudinal, observational study.
settingCommunity-dwelling subjects.
participantsMale and female subjects between 50 and 85 years of age with mild to moderate AD.
interventionNone. MEASUREMENTS: Subject dependence was assessed using the Dependence Scale (DS), cognition (ADAS-Cog, MMSE), function (DAD), behaviour (NPI) and resource utilization with the Resource Utilization in Dementia Questionnaire.
resultsThe repeated measures models confirmed a significant association between the DS and total care cost indicating an increase in cost with increasing dependence. A 1-unit increase in DS score was associated with a 28.60% increase in total care cost. Model 2 indicated that a one point change in MMSE, DAD and NPI is associated with 5.29%, 2.32% and 1.71% increase in total cost, respectively. Model 3 indicated that a one point change in ADAS-Cog, DAD and NPI is associated with a 1.74%, 2.42%and 1.62% increase in total cost, respectively.
conclusionStrategies which prevent deterioration in clinical measures or delay dependence should result in total cost savings. The quantitative relationships observed should assist in the economic assessment of interventions which effect cognition, function, behaviour and dependence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.