ArticleToxicological sciences : an official journal of the Society of Toxicology2014
Cumulative risk: toxicity and interactions of physical and chemical stressors.
Article in Toxicological sciences : an official journal of the Society of Toxicology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- MicroRNA-mediated changes contributing to benzo[a]pyrene toxicity in a 3D respiratory model for asthma.Current research in toxicology · 2026Article
- Stress, hypothalamic-pituitary-adrenal axis, hypothalamic-pituitary-gonadal axis, and aggression.Metabolic brain disease · 2024Review
- Assessing susceptibility for polycyclic aromatic hydrocarbon toxicity in anFrontiers in toxicology · 2024Article
- Unexpected Interacting Effects of Physical (Radiation) and Chemical (Bisphenol A) Treatments on Male Reproductive Functions in Mice.International journal of molecular sciences · 2021Article
- Social Susceptibility to Multiple Air Pollutants in Cardiovascular Disease.Research report (Health Effects Institute) · 2021Article
- Framing Environmental Health Decision-Making: The Struggle over Cumulative Impacts Policy.International journal of environmental research and public health · 2021Article
- Evolving Science and Practice of Risk Assessment.Risk analysis : an official publication of the Society for Risk Analysis · 2021Article
- A Cumulative Risk Perspective for Occupational Health and Safety (OHS) Professionals.International journal of environmental research and public health · 2020Article
- State-of-the-Science Review of Non-Chemical Stressors Found in a Child's Social Environment.International journal of environmental research and public health · 2019Review
- Review
- Effects of Rodent Thermoregulation on Animal Models in the Research Environment.Comparative medicine · 2018Review
- Hearing loss, lead (Pb) exposure, and noise: a sound approach to ototoxicity exploration.Journal of toxicology and environmental health. Part B, Critical reviews · 2018Review
- An Overview of Literature Topics Related to Current Concepts, Methods, Tools, and Applications for Cumulative Risk Assessment (2007-2016).International journal of environmental research and public health · 2017Review
- Connecting the Dots: Linking Environmental Justice Indicators to Daily Dose Model Estimates.International journal of environmental research and public health · 2016Article
- A Comparative Land Use-Based Analysis of Noise Pollution Levels in Selected Urban Centers of Nigeria.International journal of environmental research and public health · 2015Article
- Effects of surface-engineered nanoparticle-based dispersants for marine oil spills on the model organism Artemia franciscana.Environmental science & technology · 2014Article
- A new role for carbonic anhydrase 2 in the response of fish to copper and osmotic stress: implications for multi-stressor studies.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Recent efforts to update cumulative risk assessment procedures to incorporate nonchemical stressors ranging from physical to psychosocial reflect increased interest in consideration of the totality of variables affecting human health and the growing desire to develop community-based risk assessment methods. A key roadblock is the uncertainty as to how nonchemical stressors behave in relationship to chemical stressors. Physical stressors offer a reasonable starting place for measuring the effects of nonchemical stressors and their modulation of chemical effects (and vice versa), as they clearly differ from chemical stressors; and "doses" of many physical stressors are more easily quantifiable than those of psychosocial stressors. There is a commonly held belief that virtually nothing is known about the impact of nonchemical stressors on chemically mediated toxicity or the joint impact of coexposure to chemical and nonchemical stressors. Although this is generally true, there are several instances where a substantial body of evidence exists. A workshop titled "Cumulative Risk: Toxicity and Interactions of Physical and Chemical Stressors" held at the 2013 Society of Toxicology Annual Meeting provided a forum for discussion of research addressing the toxicity of physical stressors and what is known about their interactions with chemical stressors, both in terms of exposure and effects. Physical stressors including sunlight, heat, radiation, infectious disease, and noise were discussed in reference to identifying pathways of interaction with chemical stressors, data gaps, and suggestions for future incorporation into cumulative risk assessments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.