ReviewNature chemistry2013
The past, present and potential for microfluidic reactor technology in chemical synthesis.
Review in Nature chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 172 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
172 citing papers in PubMed.
- Review
- Femtoliter Batch Reactors for Nanofluidic Scattering Spectroscopy Analysis of Catalytic Reactions on Single Nanoparticles.Small methods · 2026Article
- Artificial Intelligence-Aided Microfluidic Cell Culture Systems.Biosensors · 2025Review
- Liquid Crystal-Driven Chemical Feeding Accelerates Condensation Reactions in Droplet Microreactors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Ultrafast Laser-Enabled 3D Glass Microchannel Reactors.Sensors (Basel, Switzerland) · 2025Review
- Research on the Design of Micromixer Based on Acoustic Streaming-Driven Sharp-Edge Structures.Sensors (Basel, Switzerland) · 2025Article
- Enhancing cell characterization with microfluidics and AI: a comprehensive review of mechanical, electrical, and hybrid techniques.Biotechnology reports (Amsterdam, Netherlands) · 2025Review
- Research and Developments of Heterogeneous Catalytic Technologies.Molecules (Basel, Switzerland) · 2025Review
- Co(II)-Mediated Catalytic Chain Transfer Polymerization (CCTP) Carried Out Under Flow Reaction Conditions and Introducing a New Method for Online GPC Monitoring.ACS polymers Au · 2025Article
- Synthesis of dendritic mesoporous silica nanoparticles by ultrasonic assisted microchannel continuous flow reaction.RSC advances · 2025Article
- Review
- Microfluidics for Electrochemical Energy Conversion and Storage: Prospects Toward Sustainable Ammonia Production.Chemical record (New York, N.Y.) · 2025Review
- A Green, Solvent- and Cation-Free Approach for Preparing 5-Fluorouracil-Loaded Alginate Nanoparticles Using Microfluidic Technology.Pharmaceutics · 2025Article
- Hyperspectral Imaging for High Throughput Optical Spectroscopy of pL Droplets.Analytical chemistry · 2025Article
- A Machine Vision Perspective on Droplet-Based Microfluidics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Microfluidic Thread-Based Analytical Platform for Reaction Screening Enabled by In Situ Thread Spray Mass Spectrometry.Analytical chemistry · 2025Article
- Continuous-Flow and Scalable Synthesis of Pd@PtThe journal of physical chemistry. C, Nanomaterials and interfaces · 2024Article
- Boosting Microfluidic Enzymatic Cascade Reactions with pH-Responsive Polymersomes by Spatio-Chemical Activity Control.Small methods · 2024Article
- Fused Deposition Modeling of Chemically Resistant Microfluidic Chips in Polyvinylidene Fluoride.Micromachines · 2024Article
- Dual-control of incubation effect for efficiently fabricating surface structures in fused silica.Nanophotonics (Berlin, Germany) · 2024Article
112 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The past two decades have seen far-reaching progress in the development of microfluidic systems for use in the chemical and biological sciences. Here we assess the utility of microfluidic reactor technology as a tool in chemical synthesis in both academic research and industrial applications. We highlight the successes and failures of past research in the field and provide a catalogue of chemistries performed in a microfluidic reactor. We then assess the current roadblocks hindering the widespread use of microfluidic reactors from the perspectives of both synthetic chemistry and industrial application. Finally, we set out seven challenges that we hope will inspire future research in this field.
Indexed as
Identifiers
24153367What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.