ReviewClinical chemistry2014
The potential role of oral fluid in antidoping testing.
Review in Clinical chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Determination of drugs of abuse in oral fluid using dried oral fluid spot assisted by 24-well plate and LC-MS/MS.Bioanalysis · 2025Review
- Detection of Cannabinoids in Oral Fluid Specimens as the Preferred Biological Matrix for a Point-of-Care Biosensor Diagnostic Device.Biosensors · 2024Review
- Comparing presumptive with direct-to-definitive drug testing in oral fluid vs. urine for a U.S. national sample of individuals misusing drugs.Drug and alcohol dependence · 2023Article
- Police officers' perspective on doping and prevention among recreational athletes: a cross-sectional study.Frontiers in sports and active living · 2023Article
- Review
- Doping in Racing Pigeons (Veterinary sciences · 2022Review
- Facilitators and barriers in preventing doping among recreational athletes: A qualitative interview study among police officers.Frontiers in public health · 2022Article
- Validation of a Bioanalytical Method for the Determination of Synthetic and Natural Cannabinoids (New Psychoactive Substances) in Oral Fluid Samples by Means of HPLC-MS/MS.Frontiers in chemistry · 2020Article
- Does oral fluid contribute to exhaled breath samples collected by means of an electret membrane?Drug testing and analysis · 2019Article
- Correlation Between Salivary Biochemical Stress Indicators and Psychological Indicators.Acta clinica Croatica · 2018Article
- Revolutionizing Therapeutic Drug Monitoring with the Use of Interstitial Fluid and Microneedles Technology.Pharmaceutics · 2017Review
- Expanding analytical options in sports drug testing: Mass spectrometric detection of prohibited substances in exhaled breath.Rapid communications in mass spectrometry : RCM · 2017Article
- Oral fluid cocaine and benzoylecgonine concentrations following controlled intravenous cocaine administration.Forensic science international · 2016Article
- Investigation of Saliva as an Alternative to Plasma Monitoring of Voriconazole.Clinical pharmacokinetics · 2015Article
- Direct drug analysis from oral fluid using medical swab touch spray mass spectrometry.Analytica chimica acta · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
backgroundCurrently, urine and blood are the only matrices authorized for antidoping testing by the World Anti-Doping Agency (WADA). Although the usefulness of urine and blood is proven, issues remain for monitoring some drug classes and for drugs prohibited only in competition. The alternative matrix oral fluid (OF) may offer solutions to some of these issues. OF collection is easy, noninvasive, and sex neutral and is directly observed, limiting potential adulteration, a major problem for urine testing. OF is used to monitor drug intake in workplace, clinical toxicology, criminal justice, and driving under the influence of drugs programs and potentially could complement urine and blood for antidoping testing in sports. CONTENT: This review outlines the present state of knowledge and the advantages and limitations of OF testing for each of the WADA drug classes and the research needed to advance OF testing as a viable alternative for antidoping testing. SUMMARY: Doping agents are either prohibited at all times or prohibited in competition only. Few OF data from controlled drug administration studies are available for substances banned at all times, whereas for some agents prohibited only in competition, sufficient data may be available to suggest appropriate analytes and cutoffs (analytical threshold concentrations) to identify recent drug use. Additional research is needed to characterize the disposition of many banned substances into OF; OF collection methods and doping agent stability in OF also require investigation to allow the accurate interpretation of OF tests for antidoping monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.