Evidence map›Paper›PMID 24152940›Full record

ArticleJournal of the International Society of Sports Nutrition2013

Thoracic aorta vasoreactivity in rats under exhaustive exercise: effects of Lycium barbarum polysaccharides supplementation.

Zhifang Zhao, Yan Luo, Guanghua Li, Lingqin Zhu, Yin Wang, Xuehong Zhang

Open access · goldAbstract read
In one paragraph

Article in Journal of the International Society of Sports Nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  7. Simple nanoliposomes encapsulatingInternational journal of nanomedicine · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhifang Zhao *Department of Physiology, School of Basic Medical Science, Ningxia Medical University, Yinchuan 750004, China.
Yan Luo *Department of Physiology, School of Basic Medical Science, Ningxia Medical University, Yinchuan 750004, China.
Guanghua LiDepartment of Physiology, School of Basic Medical Science, Ningxia Medical University, Yinchuan 750004, China.
Lingqin ZhuDepartment of Physiology, School of Basic Medical Science, Ningxia Medical University, Yinchuan 750004, China.
Yin WangDepartment of Physiology, School of Basic Medical Science, Ningxia Medical University, Yinchuan 750004, China.
Xuehong ZhangDepartment of Pediatrics, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Ningxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReduced arterial compliance is associated with an increased rate of morbidity and mortality in cardiovascular disease. Exercise is beneficial for compromised arterial compliance. However, the beneficial effects of exercise are lost with exhaustion. Lycium barbarum L. has been used in China for centuries to maintain good health. In this regard, the primary purpose of this study was to characterize the effects of the polysaccharides from Lycium barbarum (LBPs) on arterial compliance during exhaustive exercise.

methodsA four-week swimming exercise program was designed for rats, and the blood levels of malondialdehyde (MDA), super oxide dismutase (SOD), nitric oxide(NO) and heat shock protein 70(HSP70) were detected. The tension of aorta rings was measured to evaluate the response of rats on noradrenaline (NA)-induced contractions.

resultsThe rats administered LBPs showed longer swimming time until exhaustion than the control group of rats. Exercise-induced MDA elevation was repressed by LBPs supplementation. The LBPs-supplemented rats displayed a significant increase of SOD, NO, HSP70 than the non-supplemented rats. Additionally, LBPs significantly up-regulated the expression of eNOS and improved the endothelium-dependent vasodilatation of the aorta ring.

conclusionOur study proved that LBPs administration significantly inhibited the oxidative stress, and improved the arterial compliance.

Identifiers

PMID24152940
PMCPMC4015534
OpenAlexW2111788605

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.