ArticleThe ISME journal2014
Sympatric inhibition and niche differentiation suggest alternative coevolutionary trajectories among Streptomycetes.
Article in The ISME journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed, 118 citations in OpenAlex.
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- Microbial Community Structure in the Taklimakan Desert: The Importance of Nutrient Levels in Medium and Culture Methods.Biology · 2024Article
- Higher-order interactions and emergent properties of microbial communities: The power of synthetic ecology.Heliyon · 2024Review
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- Plant community richness and foliar fungicides impact soilFrontiers in microbiology · 2024Article
- Soil nutrient amendment increases the potential for inter-kingdom resource competition among foliar endophytes.ISME communications · 2024Article
- Genomic insights into an endophyticFrontiers in microbiology · 2024Article
- Antioxidant and chemoprotective potential of Streptomyces levis strain isolated from human gut.AMB Express · 2023Article
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- Environmental structure impacts microbial composition and secondary metabolism.ISME communications · 2022Article
- Network structure of resource use and niche overlap within the endophytic microbiome.The ISME journal · 2022Article
- Elevational Gradients Impose Dispersal Limitation onFrontiers in microbiology · 2022Article
- Wet-dry cycles protect surface-colonizing bacteria from major antibiotic classes.The ISME journal · 2022Article
- Article
- Plant-derived bioactive compounds produced by Streptomyces variabilis LCP18 associated with Litsea cubeba (Lour.) Pers as potential target to combat human pathogenic bacteria and human cancer cell lines.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Local adaptation, geographical distance and phylogenetic relatedness: Assessing the drivers of siderophore-mediated social interactions in natural bacterial communities.Journal of evolutionary biology · 2021Article
- Resource partitioning of phytoplankton metabolites that support bacterial heterotrophy.The ISME journal · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soil bacteria produce a diverse array of antibiotics, yet our understanding of the specific roles of antibiotics in the ecological and evolutionary dynamics of microbial interactions in natural habitats remains limited. Here, we show a significant role for antibiotics in mediating antagonistic interactions and nutrient competition among locally coexisting Streptomycete populations from soil. We found that antibiotic inhibition is significantly more intense among sympatric than allopatric Streptomycete populations, indicating local selection for inhibitory phenotypes. For sympatric but not allopatric populations, antibiotic inhibition is significantly positively correlated with niche overlap, indicating that inhibition is targeted toward bacteria that pose the greatest competitive threat. Our results support the hypothesis that antibiotics serve as weapons in mediating local microbial interactions in soil and suggest that coevolutionary niche displacement may reduce the likelihood of an antibiotic arms race. Further insight into the diverse roles of antibiotics in microbial ecology and evolution has significant implications for understanding the persistence of antibiotic inhibitory and resistance phenotypes in environmental microbes, optimizing antibiotic drug discovery and developing strategies for managing microbial coevolutionary dynamics to enhance inhibitory phenotypes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.