ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2013
Feasibility of detection and intervention for alcohol-related liver disease in the community: the Alcohol and Liver Disease Detection study (ALDDeS).
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 80 citations in OpenAlex.
- Trial
- Barriers and facilitators of implementation of liver screening in an outreach-based care pathway for people experiencing homelessness and substance use disorders: a qualitative study of clinicians' and stakeholders' perspectives.Harm reduction journal · 2026Article
- Primary Liver Cancer Trends Worldwide and in China: Analysis of GLOBOCAN 2022 Data and Disease Management Implications.Portal hypertension & cirrhosis · 2026Review
- Reducing alcohol-associated liver disease burden in the general population.The lancet. Gastroenterology & hepatology · 2025Review
- Article
- Screening for Alcohol Use Disorder Among Hospitalised Patients: Learning from a Retrospective Cohort Study in Secondary Care.Journal of clinical medicine · 2024Article
- Mental Manifestations and Biomarkers of Alcohol Consumption.Life (Basel, Switzerland) · 2024Review
- The LIVER CARE trial - screening for liver disease in individuals attending treatment for alcohol use disorder: a randomized controlled feasibility trial.Pilot and feasibility studies · 2024Article
- Hepatology consultation is associated with decreased early return to alcohol use after discharge from an inpatient alcohol use disorder treatment program.Hepatology communications · 2024Article
- Transient Elastography and Video Recovery Narrative Access to Support Recovery From Alcohol Misuse: Development of a Novel Intervention for Use in Community Alcohol Treatment Services.JMIR formative research · 2023Article
- Does knowledge of liver fibrosis affect high-risk drinking behaviour (KLIFAD): an open-label pragmatic feasibility randomised controlled trial.EClinicalMedicine · 2023Article
- Transient Elastography in Community Alcohol Services: Can It Detect Significant Liver Disease and Impact Drinking Behaviour?Biomedicines · 2022Article
- Article
- Reducing the Global Burden of Alcohol-Associated Liver Disease: A Blueprint for Action.Hepatology (Baltimore, Md.) · 2021Review
- Validation of the liver traffic light test as a predictive model for survival and development of liver-related events.JGH open : an open access journal of gastroenterology and hepatology · 2021Article
- Uncovering unsuspected advanced liver fibrosis in patients referred to alcohol nurse specialists using the ELF test.BMC gastroenterology · 2021Article
- Article
- Prediction of liver fibrosis severity in alcoholic liver disease by human microfibrillar-associated protein 4.Liver international : official journal of the International Association for the Study of the Liver · 2020Article
- Outpatient management of alcohol-related liver disease.The lancet. Gastroenterology & hepatology · 2020Review
- Alcohol consumption analysis among patients with liver disease in China.Chinese medical journal · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the past 15 years mortality rates from liver disease have doubled in the UK. Brief alcohol advice is cost effective, but clinically meaningful reductions in alcohol consumption only occur in around 1 in 10 individuals.
aimTo provide evidence that detecting early liver disease in the community is feasible, practical, and that feedback of liver risk can increase the proportion of subjects reducing alcohol consumption. DESIGN AND
settingA community feasibility study in nine general practice sites in Hampshire.
methodHazardous and harmful drinkers were identified by WHO AUDIT questionnaire and offered screening for liver fibrosis.
resultsIn total, 4630 individuals responded, of whom 1128 (24%) hazardous or harmful drinkers were offered a liver fibrosis check using the Southampton Traffic Light (STL) test; 393 (38%) attended and test results were returned by post. The STL has a low threshold for liver fibrosis with 45 (11%) red, 157 (40%) amber, and 191 (49%) green results. Follow-up AUDIT data was obtained for 303/393 (77%) and 76/153 (50%) subjects with evidence of liver damage reduced drinking by at least one AUDIT category (harmful to hazardous, or hazardous to low risk) compared with 52/150 (35%, P<0.011) subjects without this evidence; in the subset of harmful drinkers patterns (AUDIT >15), 22/34 (65%) of STL positives, reduced drinking compared with 10/29 (35%, P<0.017) STL negatives.
conclusionDetection of liver disease in the community is feasible, and feedback of liver risk may reduce harmful drinking.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.