Evidence map›Paper›PMID 24151589›Full record

Trial reportBioMed research international2013

Effects of neuromuscular electrical stimulation combined with exercises versus an exercise program on the pain and the function in patients with knee osteoarthritis: a randomized controlled trial.

Aline Mizusaki Imoto, Stella Peccin, Kelson Nonato Gomes da Silva, Lucas Emmanuel Pedro de Paiva Teixeira, Marcelo Ismael Abrahão, Virgínia Fernandes Moça Trevisani

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02802878 (Determining the Effects of the Combined Application of Electrical Stimulation and Volitional Contractions on Muscle Strength and Knee Pain and Function in Women With or at Risk for Knee Osteoarthritis), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02802878 nacompletednot on this mapstarted 2016, after this paper: background citation

Determining the Effects of the Combined Application of Electrical Stimulation and Volitional Contractions on Muscle Strength and Knee Pain and Function in Women With or at Risk for Knee Osteoarthritis

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2016 to 2016Enrolled42ConditionsKnee OsteoarthritisArmsHybrid Training using Electrodes and Joint Motion Sensors, Isokinetic Training with Isokinetic Dynamometer
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aline Mizusaki ImotoInternal Medicine Department, Federal University of São Paulo, 04023-900 São Paulo, SP, Brazil.
Stella Peccin
Kelson Nonato Gomes da Silva
Lucas Emmanuel Pedro de Paiva Teixeira
Marcelo Ismael Abrahão
Virgínia Fernandes Moça Trevisani

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the effect of 8 weeks of NMES + Ex (neuromuscular electrical stimulation combined with exercises) on pain and functional improvement in patients with knee osteoarthritis (OA) compared to exercise (Ex) alone.

designRandomized controlled trial.

settingA specialty outpatient clinic.

participantsPatients (N = 100; women = 86, men = 14; age range, 50-75 years) with knee OA.

interventionsParticipants were randomly assigned to NMES + Ex or Ex group. OUTCOME MEASURES: Numerical Rating Scale 0 to 10 (NRS) and the Timed Up and Go (TUG) test were the primary outcomes. The secondary outcomes used were the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).

resultsFollowing the interventions, a statistically significant improvement in both groups was observed in all outcomes assessed. For the comparison between the groups, no statistically significant difference was found between the NMES + Ex and the Ex groups in NRS (P = 0.52), TUG test (P = 0.12), and aspects of WOMAC: pain (P = 0.26), function (P = 0.23), and stiffness (P = 0.63).

conclusionTHE addition of NMES to exercise did not improve the outcomes assessed in knee OA patients. This study was registered at the Australian Clinical Trials Registry (ACTRN012607000357459).

Indexed as

Electric Stimulation TherapyExercise TherapyAgedAustraliaFemaleHumansMaleMiddle AgedOsteoarthritis, KneePainPain Management

Identifiers

PMID24151589
PMCPMC3787573

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.