ReviewFrontiers in psychiatry2013
Treatment approaches for interoceptive dysfunctions in drug addiction.
Review in Frontiers in psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Psychological interventions for interoception in mental health disorders: A systematic review of randomized-controlled trials.Psychiatry and clinical neurosciences · 2023Pooled it
- The relationship between mindfulness and objective measures of body awareness: A meta-analysis.Scientific reports · 2019Pooled it
- The hyper-sentient addict: an exteroception model of addiction.The American journal of drug and alcohol abuse · 2015Pooled it
- Testing the role of the posterior cingulate cortex in processing salient stimuli in cannabis users: an rTMS study.The European journal of neuroscience · 2019Trial
- The Inner Road to Happiness: A Narrative Review Exploring the Interoceptive Benefits of Exercise for Well-Being.Healthcare (Basel, Switzerland) · 2025Review
- Inconsistent Bodily Feedback? Interoceptive Sensibility Affects Internet Gaming Disorder in Emerging Adults.Behavioral sciences (Basel, Switzerland) · 2025Article
- Alcohol and alcoholism associated neurological disorders: Current updates in a global perspective and recent recommendations.World journal of experimental medicine · 2025Review
- An Overview of the Bodily Awareness Representation and Interoception: Insights and Progress in the Field of Neurorehabilitation Research.Brain sciences · 2024Review
- Physical Exercise to Redynamize Interoception in Substance use Disorders.Current neuropharmacology · 2024Article
- Ayahuasca: A review of historical, pharmacological, and therapeutic aspects.PCN reports : psychiatry and clinical neurosciences · 2023Review
- Effects of a trauma-informed mindful recovery program on comorbid pain, anxiety, and substance use during primary care buprenorphine treatment: A proof-of-concept study.The American journal on addictions · 2023Article
- Interoception Within the Context of Impulsivity and Addiction.Current addiction reports · 2023Review
- Increased insula response to interoceptive attention following mindfulness training is associated with increased body trusting among patients with depression.Psychiatry research. Neuroimaging · 2022Article
- Mindfulness-Based Interventions for the Treatment of Aberrant Interoceptive Processing in Substance Use Disorders.Brain sciences · 2022Review
- Brain Neural Underpinnings of Interoception and Decision-Making in Alzheimer's Disease: A Narrative Review.Frontiers in neuroscience · 2022Review
- Effects of moderate-intensity exercise on social health and physical and mental health of methamphetamine-dependent individuals: A randomized controlled trial.Frontiers in psychiatry · 2022Article
- Psychotherapeutic and neurobiological processes associated with ayahuasca: A proposed model and implications for therapeutic use.Frontiers in neuroscience · 2022Article
- Enhanced Resting-State Functional Connectivity With Decreased Amplitude of Low-Frequency Fluctuations of the Salience Network in Mindfulness Novices.Frontiers in human neuroscience · 2022Article
- Neural and Behavioral Correlates of Impaired Insight and Self-Awareness in Substance Use Disorder.Current behavioral neuroscience reports · 2021Article
- Repetitive transcranial magnetic stimulation as a potential treatment approach for cannabis use disorder.Progress in neuro-psychopharmacology & biological psychiatry · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
There is emerging evidence that individuals with drug addiction have dysfunctions in brain systems that are important for interoceptive processing, which include, among others, the insular and the anterior cingulate cortices. These individuals may not be expending sufficient neural resources to process perturbations of the interoceptive state but may exert over-activation of these systems when processing drug-related stimuli. As a consequence, insufficient detection and processing of interoceptive state changes may result in inadequate anticipation and preparation to adapt to environmental challenges, e.g., adapt to abstinence in the presence of withdrawal symptoms. Here, we integrate interoceptive dysfunction in drug-addicted individuals, with the neural basis for meditation and exercise to develop a heuristic to target the interoceptive system as potential treatments for drug addiction. First, it is suggested that mindfulness-based approaches can modulate both interoceptive function and insular activation patterns. Second, there is an emerging literature showing that the regulation of physical exercise in the brain involves the insula and anterior cingulate cortex and that intense physical exercise is associated with a insula changes that may provide a window to attenuate the increased interoceptive response to drug-related stimuli. It is concluded that the conceptual framework of interoceptive dysfunctions in drug addiction and the experimental findings in meditation and exercise provide a useful approach to develop new interventions for drug addiction.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.