ReviewThe Clinical biochemist. Reviews2013
HbA1c as a Diagnostic Test for Diabetes Mellitus - Reviewing the Evidence.
Review in The Clinical biochemist. Reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Could nutrient supplements provide additional glycemic control in diabetes management? A systematic review and meta-analysis of randomized controlled trials of as an add-on nutritional supplementation therapy.Archives of pharmacal research · 2022Pooled it
- Lack of Efficacy of Suvorexant in People with Insomnia and Poorly Controlled Type 2 Diabetes.Nature and science of sleep · 2023Trial
- Trial
- Trial
- Phytate Decreases Formation of Advanced Glycation End-Products in Patients with Type II Diabetes: Randomized Crossover Trial.Scientific reports · 2018Trial
- Fatal diabetic ketoacidosis associated with excessive soft drink consumption: a case report.Forensic science, medicine, and pathology · 2026Article
- Diabetes care performance across Europe: a cascade of care approach accounting for population diversity in 10 countries.BMC public health · 2026Article
- Evaluation of the relationship between glycated hemoglobin (HbA1c) levels and diabetes and other diseases: A retrospective study.Pakistan journal of medical sciences · 2026Article
- Improving Diabetes and Pre-Diabetes Detection in the UK: Insights From HbA1c Screening in an Acute Hospital's Emergency Department.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Article
- Advancement of artificial intelligence based treatment strategy in type 2 diabetes: A critical update.Journal of pharmaceutical analysis · 2025Review
- Cross-sectional and longitudinal associations between glycaemic measures and grip strength in people without diabetes in the UK Biobank cohort study.European geriatric medicine · 2025Article
- Understanding the role of metabolic syndrome in prostate cancer risk: A UK Biobank prospective cohort study.Scientific reports · 2025Article
- Association Between Glycated Hemoglobin and Diabetic Retinopathy in Individuals with Diabetes: A Focus on the Modifying Effect of Ambulatory Blood Pressure.Clinical interventions in aging · 2025Article
- Epicardial fat and insulin resistance in healthy older adults: a cross-sectional analysis.GeroScience · 2024Article
- Tools to implement measurement-based care (MBC) in the treatment of opioid use disorder (OUD): toward a consensus.Addiction science & clinical practice · 2024Article
- Seasonal variation of glycated haemoglobin and estimated average glucose in temperate South Africa.Journal of the colleges of medicine of South Africa · 2024Article
- Article
- A Critical Review of Diagnostic Strategies and Maternal Offspring Complications in Gestational Diabetes Mellitus.Cureus · 2023Review
- The inverse association between DNA gaps and HbA1c levels in type 2 diabetes mellitus.Scientific reports · 2023Article
- The effect of age and gender on HbA1c levels in adults without diabetes mellitus.Journal of medical biochemistry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evidence base in support of HbA1c as a diagnostic test for diabetes mellitus is focused on predicting a clinical outcome, considered to be the pinnacle of the Stockholm Hierarchy applied to reference intervals and clinical decision limits. In the case of diabetes, the major outcome of interest is the long term microvascular complications for which a large body of data has been accumulated, leading to the endorsement of HbA1c for diagnosis in many countries worldwide, with some variations in cut-offs and testing strategies.
Identifiers
24151343PMC3799221What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.