ReviewThe Clinical biochemist. Reviews2013
From evidence to best practice in laboratory medicine.
Review in The Clinical biochemist. Reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Evaluation of direct-to-consumer low-volume lab tests in healthy adults.The Journal of clinical investigation · 2016Trial
- Educational and Practice Needs of Laboratory Profession - Findings From an IFCC Survey.EJIFCC · 2025Article
- Drug interference with biochemical laboratory tests.Biochemia medica · 2023Review
- Components of Out-of-Pocket Expenditure and Their Relative Contribution to Economic Burden of Diseases in India.JAMA network open · 2022Article
- Appropriateness of troponin testing in emergency department at a tertiary care hospital in Saudi Arabia.Saudi medical journal · 2022Article
- Health-seeking behaviour, views and preferences of adults with suspected increased intestinal permeability: A cross-sectional survey of Australian adults.Integrative medicine research · 2022Article
- An opportunity to emphasize the relevance of laboratory medicine.Advances in laboratory medicine · 2021Article
- Project Management in Laboratory Medicine.Journal of medical biochemistry · 2019Article
- Establishing Pediatric and Adult RBC Reference Intervals With NHANES Data Using Piecewise Regression.American journal of clinical pathology · 2019Article
- Article
- Integrating unified medical language system and association mining techniques into relevance feedback for biomedical literature search.BMC bioinformatics · 2016Article
- Compliance to HIV treatment monitoring guidelines can reduce laboratory costs.Southern African journal of HIV medicine · 2016Article
- Implications of the introduction of laboratory demand management at primary care clinics in South Africa on laboratory expenditure.African journal of laboratory medicine · 2016Article
- An Unrecorded Pre-Pre-Analytical Error in Serum Iron Analysis.Journal of clinical and diagnostic research : JCDR · 2015Article
- Add to cart?Canadian family physician Medecin de famille canadien · 2015Article
- Article
- Thrombelastographic pattern recognition in renal disease and trauma.The Journal of surgical research · 2015Article
- Use and Utility of Hemostatic Screening in Adults Undergoing Elective, Non-Cardiac Surgery.PloS one · 2015Article
- Commercial screening tests: Beneficial or a hypnosis to advertisements?Journal of postgraduate medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laboratory tests offer value if they provide benefit to patients at acceptable costs. Laboratory testing is one of the most widely used diagnostic interventions supporting medical decisions, yet evidence demonstrating its value and impact on health outcomes is limited. This contributes to wide variations in test utilisation including underdiagnosis, overdiagnosis and misdiagnosis, which may impact the quality and the clinical- and cost-effectiveness of care and patient safety. Therefore implementing evidence into the care of patients is a moral and social imperative to laboratory professionals and all health care staff. This review investigates the reasons research does not get into practice, or only does with a very long delay. Apart from reviewing the common barriers to implementation, it also discusses the drivers of inappropriate test utilisation. By reviewing the theoretical and practical aspects of implementation science, recommendations are made for approaches that are thought to be most effective and that can be adopted to close the gap between evidence and practice, and to facilitate evidence-based laboratory medicine. Passive dissemination of the evidence and educational interventions are insufficient and do not offer sustainable solutions. A multifaceted and individualised implementation strategy, including individually tailored academic detailing, reminder systems, clinical decision support systems, feedback on performance, and participation of doctors and laboratory professionals in quality improvement activities addressing test selection and interpretation and in clinical audits, has greater potential for success. Examples of these initiatives at the laboratory and clinical interface are provided with links to valuable resources.
Identifiers
24151341PMC3799219What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.