ArticleJournal of oncology practice2013
Effect of medical oncologists' attitudes on accrual to clinical trials in a community setting.
Article in Journal of oncology practice, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Priorities for Rural Lymphoma Survivors: A Qualitative Study.Clinical lymphoma, myeloma & leukemia · 2020Trial
- Financial Burden of Cancer Clinical Trial Participation and the Impact of a Cancer Care Equity Program.The oncologist · 2016Trial
- Physician- and Practice-Level Variation in Clinical Trial Participation Among Patients With Advanced Cancer.JAMA network open · 2026Article
- A multicenter survey on BRAF screening for the implementation of perioperative cancer genomic medicine for resectable colorectal oligometastases.International journal of clinical oncology · 2026Article
- Enhancing biomarker based oncology trial matching using large language models.NPJ digital medicine · 2025Article
- Development of clinical research networks in rural America: Our experience from the Accelerating COVID-19 Therapeutic Interventions and Vaccines-1 trialau.Journal of clinical and translational science · 2025Article
- Barriers to Clinical Trial Implementation Among Community Care Centers.JAMA network open · 2024Article
- Piloting an automated clinical trial eligibility surveillance and provider alert system based on artificial intelligence and standard data models.BMC medical research methodology · 2023Observational
- Barriers for cancer clinical trial enrollment: A qualitative study of the perspectives of healthcare providers.Contemporary clinical trials communications · 2022Article
- Understanding the Barriers to Pediatric Oncologist Engagement and Accrual to Clinical Trials in National Cancer Institute-Designated Community Oncology Research Programs.JCO oncology practice · 2020Article
- Barriers to Participation in Therapeutic Clinical Trials as Perceived by Community Oncologists.JCO oncology practice · 2020Article
- Review
- Disparities in pediatric acute myeloid leukemia (AML) clinical trial enrollment.Leukemia & lymphoma · 2019Article
- Automatic trial eligibility surveillance based on unstructured clinical data.International journal of medical informatics · 2019Article
- Patient-Pivoted Automated Trial Eligibility Pipeline: The First of Three Phases in a Modular Architecture.Studies in health technology and informatics · 2019Article
- Conceptual Model for Accrual to Cancer Clinical Trials.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019Article
- Premature Clinical Trial Discontinuation in the Era of Immune Checkpoint Inhibitors.The oncologist · 2018Article
- Recruitment practices for U.S. minority and underserved populations in NRG oncology: Results of an online survey.Contemporary clinical trials communications · 2018Article
- Leveraging National Cancer Institute Programmatic Collaboration for Uterine Cervix Cancer Patient Accrual in Puerto Rico.Frontiers in oncology · 2018Article
- Access to clinical trials among oncology patients: results of a cross sectional survey.BMC cancer · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeOncology clinical trials (OCTs) are crucial in evaluating new cancer treatments, but only 2% to 3% of US adult patients with cancer enter OCTs. This study assessed barriers to participation in clinical trials among oncologists in a large integrated health care delivery system with an active clinical trials program. Although many studies have identified major physician barriers to enrollment, few have examined how these barriers affect actual trial accrual.
methodsUsing information from a mailed survey, we examined the effect of oncologists' attitudes, beliefs, experiences, sociodemographic factors, and practice characteristics on clinical trial accrual in the 2 years following the survey. We identified relationships between these variables and subsequent clinical trial accrual using correlations and mixed effects models.
resultsA construct combining questions that assessed oncologist attitudes, beliefs, and experiences substantially influenced OCT enrollment (r = .51; P < .0001). This construct included awareness of open clinical trials and specific eligible patients, as well as the practice of initiating a discussion about OCTs with most eligible patients. This broad concept of awareness had the greatest correlation with enrollment and mediated the effect on enrollment of other values and beliefs, such as welcoming a patient's initiation of a trial discussion and valuing the support of research nurses and coordinators.
conclusionEven in a health care setting with an active clinical trials program, substantial research personnel, infrastructure support, and widespread access to trials among oncologists and patients, oncologists' participation remains quite variable. Oncologist values, beliefs, and awareness of clinical trials play an important role in OCT accrual.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.