ArticleThe Journal of infectious diseases2014
The global transmission network of HIV-1.
Article in The Journal of infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 157 papers, 2 of them syntheses that pooled it.
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Who cites it
157 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Advances in research of HIV transmission networks.Chinese medical journal · 2020Pooled it
- Defining HIV-1 transmission clusters based on sequence data.AIDS (London, England) · 2017Pooled it
- Trial
- Current and historic HIV-1 molecular epidemiology in paediatric and adult population from Kinshasa in the Democratic Republic of Congo.Scientific reports · 2020Trial
- Trial
- Ultrasensitive single-genome sequencing reveals strong purifying selection in acute HIV-1 infection.bioRxiv : the preprint server for biology · 2026Article
- Pretreatment HIV-1 drug resistance and molecular subtype characteristics among newly diagnosed individuals in Guangxi, China.AIDS research and therapy · 2026Article
- Acquired HIV-1 Drug Resistance and Molecular Transmission Networks in Zhongwei, Ningxia, China.Viruses · 2026Article
- HIV Transmission Dynamics in Greater Mexico City are Shaped by Dense Spatial Mixing.Research square · 2026Article
- HIV epidemic and needs beyond fast-track cities: a transmission network analysis to study the dynamics of HIV clusters in a French region near Paris.Microbiology spectrum · 2026Article
- Brief Report: National HIV Molecular Cluster Detection Supports Local Cluster Detection.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- HIV Transmission Dynamics in Greater Mexico City are Shaped by Dense Spatial Mixing.medRxiv : the preprint server for health sciences · 2026Article
- Advancing Precision Public Health: an implementation science framework for HIV Cluster Detection and Response driven by molecular epidemiology.Frontiers in public health · 2026Article
- Phylogenetics and molecular evolution to understand and curb the HIV pandemic.Nature reviews. Microbiology · 2026Review
- A graph homomorphism approach for unraveling histories of metastatic cancers and viral outbreaks under evolutionary constraints.Nature communications · 2025Article
- Detecting Evolutionary Change-Points with Branch-Specific Substitution Models and Shrinkage Priors.ArXiv · 2025Article
- Detecting Evolutionary Change-Points with Branch-Specific Substitution Models and Shrinkage Priors.Research square · 2025Article
- Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United States.Emerging infectious diseases · 2025Article
- Transmission dynamics of the 2022 mpox epidemic in New York City.Nature medicine · 2025Article
- Characteristics of molecular epidemiology and transmitted drug resistance among newly diagnosed HIV-1 infections in Lishui, China from 2020 to 2023.Virology journal · 2025Article
97 more citing papers are in PubMed but not listed here.
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7 authors.
Funding
Abstract
Human immunodeficiency virus type 1 (HIV-1) is pandemic, but its contemporary global transmission network has not been characterized. A better understanding of the properties and dynamics of this network is essential for surveillance, prevention, and eventual eradication of HIV. Here, we apply a simple and computationally efficient network-based approach to all publicly available HIV polymerase sequences in the global database, revealing a contemporary picture of the spread of HIV-1 within and between countries. This approach automatically recovered well-characterized transmission clusters and extended other clusters thought to be contained within a single country across international borders. In addition, previously undescribed transmission clusters were discovered. Together, these clusters represent all known modes of HIV transmission. The extent of international linkage revealed by our comprehensive approach demonstrates the need to consider the global diversity of HIV, even when describing local epidemics. Finally, the speed of this method allows for near-real-time surveillance of the pandemic's progression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.