ArticleJournal of genetic counseling2014
A genetic counselor's guide to using next-generation sequencing in clinical practice.
Article in Journal of genetic counseling, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03548779 (North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2), which is not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2
Who cites it
17 citing papers in PubMed.
- Voices in practice: Exploring genetic counseling ethical, cultural, social, and religious dynamics in the UAE.Journal of genetic counseling · 2025Article
- Normative Issues in Next Generation Sequencing Gene Testing.Development & reproduction · 2023Article
- Interventions addressing genetic disease burdens within selected countries in the MENA region: a scoping review.Journal of community genetics · 2023Article
- The psychosocial and service delivery impact of genomic testing for inherited retinal dystrophies.Journal of community genetics · 2019Article
- Psychological adaptation to diagnostic genomic sequencing results: The role of hope fulfillment.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2019Article
- Developing a genomics rotation: Practical training around variant interpretation for genetic counseling students.Journal of genetic counseling · 2019Article
- Genetic Counseling in the Era of Genomics: What's all the Fuss about?Journal of genetic counseling · 2018Article
- Implementation of personalized medicine in Central-Eastern Europe: pitfalls and potentials based on citizen's attitude.The EPMA journal · 2018Article
- Not the End of the Odyssey: Parental Perceptions of Whole Exome Sequencing (WES) in Pediatric Undiagnosed Disorders.Journal of genetic counseling · 2016Article
- Patient hopes for diagnostic genomic sequencing: roles of uncertainty and social status.European journal of human genetics : EJHG · 2016Article
- Visual programming for next-generation sequencing data analytics.BioData mining · 2016Review
- Disorders of sex development: effect of molecular diagnostics.Nature reviews. Endocrinology · 2015Review
- How can psychological science inform research about genetic counseling for clinical genomic sequencing?Journal of genetic counseling · 2015Article
- Characterizing Participants in the ClinSeq Genome Sequencing Cohort as Early Adopters of a New Health Technology.PloS one · 2015Article
- Identification of Genetic Alterations, as Causative Genetic Defects in Long QT Syndrome, Using Next Generation Sequencing Technology.PloS one · 2014Article
- Multigene Panel Testing for Hereditary Cancer Risk.Journal of the advanced practitioner in oncologyReview
- Understanding the Basics of NGS: From Mechanism to Variant Calling.Current genetic medicine reportsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in next-generation sequencing (NGS) and rapid reductions in cost have increased the use of such technologies in research and clinical practice. However, many barriers exist to translating NGS for routine clinical use, including issues related to the interpretation of results, and the potential to find results that are secondary or incidental to the specific application of NGS. Nonetheless, NGS has become sufficiently affordable to be offered by several clinical laboratories, and increasingly it is becoming an attractive and viable option for clinicians and patients. This article reviews current NGS technologies, highlighting the information genetic counselors need to know to make informed-decisions about utilizing NGS in the clinic, and underscoring the impact of this new testing modality on the practice of genetic counseling.
Indexed as
Identifiers
24151055What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.