ArticleAngewandte Chemie (International ed. in English)2013
Minimum set of cytochromes P450 for reconstituting the biosynthesis of camalexin, a major Arabidopsis antibiotic.
Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Reaction Engineering of In Vitro Natural Product Biosynthesis: Challenges and Strategies.Chembiochem : a European journal of chemical biology · 2025Review
- Cyanogenic millipede genome illuminates convergent evolution of cyanogenesis-related enzymes.PLoS genetics · 2025Article
- Glutathione in the Biosynthesis of Glutazoline Teredinibactins.Organic letters · 2025Article
- Mechanistic Perspective on C-N and C-S Bond Construction Catalyzed by Cytochrome P450 Enzymes.ACS bio & med chem Au · 2025Review
- A developmental gradient reveals biosynthetic pathways to eukaryotic toxins in monocot geophytes.Cell · 2024Article
- Total Synthesis FacilitatesJournal of the American Chemical Society · 2024Article
- Metabolic link between auxin production and specialized metabolites in Sorghum bicolor.Journal of experimental botany · 2023Article
- Protocorm-like-body extract ofFrontiers in plant science · 2022Article
- Genome-Wide Identification and Analyses of Drought/Salt-Responsive CytochromeInternational journal of molecular sciences · 2021Article
- Article
- Transcriptome analysis of early stages of sorghum grain mold disease reveals defense regulators and metabolic pathways associated with resistance.BMC genomics · 2021Article
- RNA-Sequencing in Resistant (QL3) and Susceptible (Theis) Sorghum Cultivars Inoculated With Johnsongrass Isolates ofFrontiers in genetics · 2021Article
- The Versatile Roles of Sulfur-Containing Biomolecules in Plant Defense-A Road to Disease Resistance.Plants (Basel, Switzerland) · 2020Review
- Aldoxime Metabolism Is Linked to Phenylpropanoid Production inFrontiers in plant science · 2020Article
- The Formation of a Camalexin Biosynthetic Metabolon.The Plant cell · 2019Article
- Expansion of a core regulon by transposable elements promotes Arabidopsis chemical diversity and pathogen defense.Nature communications · 2019Article
- Plant-derived coumarins shape the composition of anProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Hierarchical and Dynamic Regulation of Defense-Responsive Specialized Metabolism by WRKY and MYB Transcription Factors.Frontiers in plant science · 2019Article
- Identification and functional analysis of two P450 enzymes of Gossypium hirsutum involved in DMNT and TMTT biosynthesis.Plant biotechnology journal · 2018Article
- GlutathioneFrontiers in plant science · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Bringing it all together: The missing key step in the biosynthesis of camalexin was uncovered by in vitro biochemical characterization. The coupling of Trp- and Cys-derived fragments through CS bond formation is promoted by an unusual cytochrome P450 CYP71A13. The in vitro reconstitution of the camalexin biosynthesis (left) from Trp and Cys was achieved using just three cytochromes P450. IAN=indole-3-acetonitrile.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.